Wenbao Yu, PhD
Locations: Main Building
About Wenbao Yu, PhD
Titles
Research Assistant Professor
Professor in Oncology, Perelman School of Medicine at the University of Pennsylvania
Leadership and Memberships
Memberships in Professional Organizations
2020-present, Human Tumor Atlas Network
Education & training
Graduate Degree
PhD in Statistics - Chonnam National University, South Korea (Statistics)
MS in Computational Mathematics - University of Science and Technology of China, China
Fellowship
Postdoctoral Fellow - Center for Childhood Cancer Research, Children's Hospital of Philadelphia
Postdoctoral Fellow - Department of Statistics, Seoul National University
Publications
Publications
2021
Chen, G. M., Chen, C., Das, R. K., Gao, P., ..., Yu, W., ... & Tan, K. : Integrative bulk and single-cell profiling of pre-manufacture T-cell populations reveals factors mediating long-term persistence of CAR T-cell therapy. Cancer Discovery Page: doi: 10.1158, Apr 2021 Notes: epub ahead of print.
2020
Yu, W., Uzun, Y., Zhu, Q., Chen, C., & Tan, K.: scATAC-pro: a comprehensive workbench for single-cell chromatin accessibility sequencing data. Genome Biology 21(94): doi: 10.1186, Apr 2020 Notes: online pub.
Zhu, Q., Gao, P., ..., Yu, W., ... & Tan, K.: Developmental trajectory of prehematopoietic stem cell formation from endothelium. Blood 136(7): 845-856, 2020.
2019
Chen, C., Yu, W., Tober, J., Gao, P., He, B., Lee, K., ... & Tan, K. : Spatial genome re-organization between fetal and adult hematopoietic stem cells. Cell Reports 29(12): 4200-4211, 2019 Notes: Co-first author.
2018
Lee, S., Son, D., Kim, Y., Yu, W., & Park, T.: Unified Cox model based multifactor dimensionality reduction method for gene-gene interaction analysis of the survival phenotype. BigData Mining 11(27): doi: 10.1186, Dec 2018 Notes: online pub.
Yu, W., Kim, J. K., & Park, T. : Estimation of Area Under the ROC Curve under nonignorable verification bias. Statistica Sinica 28(4): 2149-2166, 2018.
2017
Yu, W., He, B., & Tan, K.: Identifying topologically associating domains and subdomains by Gaussian mixture model and proportion test. Nature communications 8(535): 535, Sep 2017.
2016
Lee, S., Son, D., Yu, W., & Park, T.: Gene-Gene Interaction Analysis for the Accelerated Failure Time Model Using a Unified Model-Based Multifactor Dimensionality Reduction Method. Genomics & Informatics 14(4): 166-172, 2016.
Yu, W., Lee, S., & Park, T.: A unified model based multifactor dimensionality reduction framework for detecting gene-gene interactions. Bioinformatics 32(17): i605-i610, 2016.
2015
Wang, X., Yu, W., & Zheng, L.: The dynamics of NF-κB pathway regulated by circadian clock. Mathematical Bioscience 260: 47-53, 2015.
Yu, W., & Park, T.: Two simple algorithms on linear combination of multiple biomarkers to maximize partial area under the ROC curve. Computational Statistics & Data Analysis 88: 15-27, 2015.
Yu, W., Kwon, M.S., & Park. T.: Multivariate quantitative multifactor dimensionality reduction for detecting gene-gene interactions. Human heredity 79(3-4): 168-181, 2015.
Yu, W., Park, E., & Chang, Y. C. I.: Comparison of paired ROC curves through a two-stage test. Journal of biopharmaceutical statistics 25(5): 881-902, 2015.
2014
Shi, F., Yu, W., & Wang, X.: Bistable Switch in let-7 miRNA Biogenesis Pathway Involving Lin28. International Journal of Molecular Science 15(10): 19119-33, 2014.
Yu, W., & Park, T.: AucPR: An AUC-based approach using penalized regression for disease prediction with high-dimensional omics data. BMC genomics 15(S1): doi: 10.1186, 2014 Notes: online pub.
Yu, W., Ivan Chang, Y. C., & Park, E.: A modified area under the ROC curve and its application to marker selection and classification. Journal of the Korean Statistical Society 43(2): 161-175, 2014.