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Hyun-Duck Nah, DMD, MSD, PhD

Hyun-Duck Nah, DMD, MSD, PhD

Hyun-Duck Nah, DMD, MSD, PhD

Hyun-Duck Nah-Cederquist, DMD, PhD, is Director of Craniofacial Orthodontics in the Division of Plastic and Reconstructive Surgery at Children's Hospital of Philadelphia.

Locations: Main Building


215-590-2208

About Hyun-Duck Nah, DMD, MSD, PhD

Titles

Craniofacial Orthodontist

Research Associate Professor of Surgery, Perelman School of Medicine at the University of Pennsylvania
Clinical Associate Professor, University of Pennsylvania School of Dental Medicine, Philadelphia PA

Awards and Honors

2010-2011, Chair, Council of Scientific Affairs, AAO
2010-2011, President, Craniofacial Biology Group, IADR/AADR
2009-2010, President-elect, Craniofacial Biology Group, IADR/AADR
2008-2009, Vice -President, Craniofacial Biology Group, International Association for Dental Research (IADR) and AADR
2004, Honorary Committee Member, The Arthritis Foundation Symposium, Eastern Pennsylvania Chapter
2000, Stewart J. McCracken Award, Arthritis Foundation, Eastern Penna. Chapter
1996, Young Investigator's Award, American Society for Bone and Mineral Research
1996, Caulk/Dentsply Award, American Association for Dental Research
1994, Young Investigator Award, East Coast Connective Tissue Society
1984-1987, University Fellowship, Univ. of Connecticut School of Dental Medicine
1981, Alumni Association Award, Seoul National Univ. School of Dental Medicine
1980, Korean delegate to the Convention of the Asian Pacific Dental Student Association, Singapore
1978, Delegate of the Korean Dental Student Association to the Congress of the International Association of Dental Students, Cleveland, OH, USA
1975- 1980, Scholarship for Academic Distinction, Seoul National University

Leadership and Memberships

Memberships in Professional Organizations

International

1984-present, International Association for Dental Research
1979, Asian Pacific Dental Student Association

National

2005-present, American Cleft Palate Association
2001-present, American Dental Association
1996-present, American Society for Bone and Mineral Research
1989-present, American Association for the Advancement of Science
1981-present, American Association of Orthodontists

Editorial and Academic Positions

Editorial Positions

2010-present, Frontiers in Craniofacial Biology, Editorial Board,
2005-present, Orthodontics and Craniofacial Research, Editorial Board
1998-present, American Journal of Orthodontics and Dentofacial Orthopedics, referee

Reviewer

American Journal of Orthodontics and Dentofacial Orthopedics
Annals of Biomedical Engineering
Bone
Cell Transplantation
Clinical Orthodontics and Research
Connective Tissue Research
Frontiers in Bioscience
Frontiers in Physiology
Journal of Biological Chemistry
Journal of Cellular Biochemistry
Journal of Cellular Biology
Journal of Dental Research
Journal of Orthopaedic Research
Tissue Engineering

Academic and Institutional Committees

2011-2015, Institutional Animal Care and Use Committee, The Children’s Hospital of Philadelphia, Philadelphia, PA

Education & training

Graduate Degree

MSD in Orthodontics - Case Western Reserve University, Cleveland, OH
PhD in Molecular Biology - University of Connecticut Health Center, Farmington, CT 

Medical Degree

DDS in Dental Medicine - Seoul National University, Seoul, South Korea (graduated summa cum laude)
DMD in Dental Medicine - University of Pennsylvania, Philadelphia, PA

Residency

Orthodontics - Case Western Reserve University, Cleveland, OH

Fellowship

Clinical Fellow in Orthodontics - University of Connecticut Health Center, Hartford, CT
Postdoctoral Fellow in Biochemistry - School of Dental Medicine, University of Pennsylvania, Philadelphia, PA

Additional Training

Postdoctoral Fellow with Department of Biochemistry - University of Pennsylvania, Philadelphia, PA

Publications

Publications

2018

Ahn NJ, Stratigis JD, Coons BE, Flake AW, Nah-Cederquist HD, Peranteau WH. Intravenous and Intra-amniotic In Utero Transplantation in the Murine Model. J Vis Exp. 2018 Oct 9;(140). doi: 10.3791/58047. PubMed PMID: 30371676; PubMed Central PMCID: PMC6235462.

Kurio N, Saunders C, Bechtold TE, Salhab I, Nah HD, Sinha S, Billings PC, Pacifici M, Koyama E. Roles of Ihh signaling in chondroprogenitor function in postnatal condylar cartilage. Matrix Biol. 2018 Apr;67:15-31. doi: 10.1016/j.matbio.2018.02.011. Epub 2018 Feb 12. PubMed PMID: 29447948; PubMed Central PMCID: PMC5910228.

2016

Bechtold, T., Saunders, C., Decker, RS., Billings, PC., Um, HB., Naiga Cottingham, N., Kurio, N., Salhab, I; Pacifici, M., Nah, HD., Koyama, E. 2016. Osteophyte formation and matrix mineralization in a TMJ osteoarthritis mouse model are associated with ectopic hedgehog signaling. Matrix Biol, in press.

Chen I, Salhab I, Setzer FC, Kim S, Nah HD. A New Calcium Silicate-based Bioceramic Material Promotes Human Osteo- and Odontogenic Stem Cell Proliferation and Survival via the Extracellular Signal-regulated Kinase Signaling Pathway. J Endod. 2016 Mar;42(3):480-6. doi: 10.1016/j.joen.2015.11.013. Epub 2016 Jan 6. PubMed PMID: 26778265.

2015

Chen I, Karabucak B, Wang C, Wang HG, Koyama E, Kohli MR, Nah HD, Kim S. Healing after root-end microsurgery by using mineral trioxide aggregate and a new calcium silicate-based bioceramic material as root-end filling materials in dogs. J Endod. 2015 Mar;41(3):389-99. doi: 10.1016/j.joen.2014.11.005. Epub 2015 Jan 14. PubMed PMID: 25596728; PubMed Central PMCID: PMC4415855.

2014

Gerety PA, Wink JD, Sherif RD, Clarke N, Nah HD, Taylor JA. Treatment of large calvarial defects with bone transport osteogenesis: a preclinical sheep model. J Craniofac Surg. 2014 Sep;25(5):1917-22. doi: 10.1097/SCS.0000000000000987. PubMed PMID: 25119411.

Wink JD, Gerety PA, Sherif RD, Lim Y, Clarke NA, Rajapakse CS, Nah HD, Taylor JA. Sustained delivery of rhBMP-2 by means of poly(lactic-co-glycolic acid) microspheres: cranial bone regeneration without heterotopic ossification or craniosynostosis. Plast Reconstr Surg. 2014 Jul;134(1):51-9. doi: 10.1097/PRS.0000000000000287. PubMed PMID: 24622573; PubMed Central PMCID: PMC4105220.

2013

Caselli A, Olson TS, Otsuru S, Chen X, Hofmann TJ, Nah HD, Grisendi G, Paolucci P, Dominici M, Horwitz EM. IGF-1-mediated osteoblastic niche expansion enhances long-term hematopoietic stem cell engraftment after murine bone marrow transplantation. Stem Cells. 2013 Oct;31(10):2193-204. doi: 10.1002/stem.1463. PubMed PMID: 23818291.

2012

Siclari VA, Zhu J, Akiyama K, Liu F, Zhang X, Chandra A, Nah HD, Shi S, Qin L. Mesenchymal progenitors residing close to the bone surface are functionally distinct from those in the central bone marrow. Bone. 2013 Apr;53(2):575-86. doi: 10.1016/j.bone.2012.12.013. Epub 2012 Dec 27. PubMed PMID: 23274348; PubMed Central PMCID: PMC3674849.

Wu C, Endo M, Yang BH, Radecki MA, Davis PF, Zoltick PW, Spivak RM, Flake AW, Kirschner RE, Nah HD. Intra-amniotic transient transduction of the periderm with a viral vector encoding TGFβ3 prevents cleft palate in Tgfβ3(-/-) mouse embryos. Mol Ther. 2013 Jan;21(1):8-17. doi: 10.1038/mt.2012.135. Epub 2012 Oct 23. PubMed PMID: 23089732; PubMed Central PMCID: PMC3538297.

Nah HD, Koyama E, Agochukwu NB, Bartlett SP, Muenke M. Phenotype profile of a genetic mouse model for Muenke syndrome. Childs Nerv Syst. 2012 Sep;28(9):1483-93. doi: 10.1007/s00381-012-1778-9. Epub 2012 Aug 8. PubMed PMID: 22872265; PubMed Central PMCID: PMC4131982.

McGrath J, Gerety PA, Derderian CA, Steinbacher DM, Vossough A, Bartlett SP, Nah HD, Taylor JA. Differential closure of the spheno-occipital synchondrosis in syndromic craniosynostosis. Plast Reconstr Surg. 2012 Nov;130(5):681e-689e. doi: 10.1097/PRS.0b013e318267d4c0. PubMed PMID: 22777037.

2011

Kim SG, Kim SG, Viechnicki B, Kim S, Nah HD. Engineering of a periodontal ligament construct: cell and fibre alignment induced by shear stress. J Clin Periodontol. 2011 Dec;38(12):1130-6. doi: 10.1111/j.1600-051X.2011.01790.x. Epub 2011 Sep 27. PubMed PMID: 22092876.

Laurita J, Koyama E, Chin B, Taylor JA, Lakin GE, Hankenson KD, Bartlett SP, Nah HD. The Muenke syndrome mutation (FgfR3P244R) causes cranial base shortening associated with growth plate dysfunction and premature perichondrial ossification in murine basicranial synchondroses. Dev Dyn. 2011 Nov;240(11):2584-96. doi: 10.1002/dvdy.22752. PubMed PMID: 22016144.

2010

Marshall SD, Currier GF, Hatch NE, Huang GJ, Nah HD, Owens SE, Shroff B, Southard TE, Suri L, Turpin DL. Ask us. Self-ligating bracket claims. Am J Orthod Dentofacial Orthop. 2010 Aug;138(2):128-31. PubMed PMID: 20715337.

McDonald-McGinn DM, Feret H, Nah HD, Bartlett SP, Whitaker LA, Zackai EH. Metopic craniosynostosis due to mutations in GLI3: A novel association. Am J Med Genet A. 2010 Jul;152A(7):1654-60. doi: 10.1002/ajmg.a.33495. PubMed PMID: 20583172.

Ang BU, Spivak RM, Nah HD, Kirschner RE. Dura in the pathogenesis of syndromic craniosynostosis: fibroblast growth factor receptor 2 mutations in dural cells promote osteogenic proliferation and differentiation of osteoblasts. J Craniofac Surg. 2010 Mar;21(2):462-7. doi: 10.1097/SCS.0b013e3181cfe9a0. PubMed PMID: 20489451.

Zajac A, Baek SH, Salhab I, Radecki MA, Kim S, Hakonarson H, Nah HD. Novel ANKH mutation in a patient with sporadic craniometaphyseal dysplasia. Am J Med Genet A. 2010 Mar;152A(3):770-6. doi: 10.1002/ajmg.a.33317. PubMed PMID: 20186813; PubMed Central PMCID: PMC2944898.

2009

Grant SF, Wang K, Zhang H, Glaberson W, Annaiah K, Kim CE, Bradfield JP, Glessner JT, Thomas KA, Garris M, Frackelton EC, Otieno FG, Chiavacci RM, Nah HD, Kirschner RE, Hakonarson H. A genome-wide association study identifies a locus for nonsyndromic cleft lip with or without cleft palate on 8q24. J Pediatr. 2009 Dec;155(6):909-13. doi: 10.1016/j.jpeds.2009.06.020. Epub 2009 Aug 4. PubMed PMID: 19656524.

Suri L, Huang G, English JD Jr, Owen S, Nah HD, Riolo ML, Shroff B, Southard TE, Turpin DL. Ask us. Topical fluoride treatment. Am J Orthod Dentofacial Orthop. 2009 May;135(5):561-3. Review. PubMed PMID: 19412990.

2008

Marshall SD, English JD Jr, Huang GJ, Messersmith ML, Nah HD, Riolo ML, Shroff B, Southard TE, Suri L, Turpin DL. Ask us. Long-term stability of maxillary expansion. Am J Orthod Dentofacial Orthop. 2008 Jun;133(6):780-1. doi: 10.1016/j.ajodo.2008.02.001. PubMed PMID: 18538225.

Lin IC, Smartt JM Jr, Nah HD, Ischiropoulos H, Kirschner RE. Nitric oxide stimulates proliferation and differentiation of fetal calvarial osteoblasts and dural cells. Plast Reconstr Surg. 2008 May;121(5):1554-66; discussion 1567-9. doi: 10.1097/PRS.0b013e31816c3bd7. PubMed PMID: 18453977.

2007

Lin IC, Slemp AE, Hwang C, Sena-Esteves M, Nah HD, Kirschner RE. Dihydrotestosterone stimulates proliferation and differentiation of fetal calvarial osteoblasts and dural cells and induces cranial suture fusion. Plast Reconstr Surg. 2007 Oct;120(5):1137-47. PubMed PMID: 17898587.

Loomes KM, Stevens SA, O'Brien ML, Gonzalez DM, Ryan MJ, Segalov M, Dormans NJ, Mimoto MS, Gibson JD, Sewell W, Schaffer AA, Nah HD, Rappaport EF, Pratt SC, Dunwoodie SL, Kusumi K. Dll3 and Notch1 genetic interactions model axial segmental and craniofacial malformations of human birth defects. Dev Dyn. 2007 Oct;236(10):2943-51. Erratum in: Dev Dyn. 2008 Jun;237(6):1754. PubMed PMID: 17849441.

Cabiling DS, Kim E, Yan D, Jacob S, Nah HD, Kirschner RE. Differential effects of TGF-beta isoforms on murine fetal dural cells and calvarial osteoblasts. Plast Reconstr Surg. 2007 Sep;120(3):614-24. PubMed PMID: 17700112.

2005

Mao JJ, Nah HD. More research needed to understand how orthodontists communicate with cells. Am J Orthod Dentofacial Orthop. 2005 Apr;127(4):400. PubMed PMID: 15821679.

Fakhry A, Ratisoontorn C, Vedhachalam C, Salhab I, Koyama E, Leboy P, Pacifici M, Kirschner RE, Nah HD. Effects of FGF-2/-9 in calvarial bone cell cultures: differentiation stage-dependent mitogenic effect, inverse regulation of BMP-2 and noggin, and enhancement of osteogenic potential. Bone. 2005 Feb;36(2):254-66. PubMed PMID: 15780951.

Choi KY, Kim HJ, Lee MH, Kwon TG, Nah HD, Furuichi T, Komori T, Nam SH, Kim YJ, Kim HJ, Ryoo HM. Runx2 regulates FGF2-induced Bmp2 expression during cranial bone development. Dev Dyn. 2005 May;233(1):115-21. PubMed PMID: 15765505.

2004

Mao JJ, Nah HD. Growth and development: hereditary and mechanical modulations. Am J Orthod Dentofacial Orthop. 2004 Jun;125(6):676-89. Review. PubMed PMID: 15179392.

2003

Ratisoontorn C, Fan GF, McEntee K, Nah HD. Activating (P253R, C278F) and dominant negative mutations of FGFR2: differential effects on calvarial bone cell proliferation, differentiation, and mineralization. Connect Tissue Res. 2003;44 Suppl 1:292-7. PubMed PMID: 12952211.

2000

Nicozisis JL, Nah-Cederquist HD, Tuncay OC. Relaxin affects the dentofacial sutural tissues. Clin Orthod Res. 2000 Nov;3(4):192-201. PubMed PMID: 11553074.

Lectures by Invitation

2016

Craniofacial Orthodontics: One patient at a time. Beijing University

Cleft lip and Palate: Disease mechanisms, Genetic animal models and In utero gene-mediated rescue approach, Beijing University

Books

Kirschner RE, Nah HD. Craniofacial growth: genetic and morphological processes in craniosynostosis. In: Duyuron B, editor.  Plastic surgery. 2008

Patient experience rating

(based on 128 submissions)

  • Clear Explanation
    4.9 of 5
  • Showed Concern
    4.9 of 5
  • Included in decisions
    4.9 of 5
  • Would recommend
    4.9 of 5
  • Discussion of Proposed Treatment
    4.9 of 5
Learn about the patient experience rating system

Comments

  • Dr. Nah was very knowledgeable and helpful!

    5 of 5
    Jun 12, 2024
  • Dr Nah is wonderful, very thorough and compassionate. It was worth the wait!

    5 of 5
    Mar 07, 2024
  • Dr. Nah is wonderful. We traveled 3 hours to see her & will continue to do so.

    5 of 5
    Jan 21, 2024
  • Dr. Nah and her team are excellent and have served our family at the highest levels for many years.

    5 of 5
    Dec 16, 2023
  • Dr. Nah is the greatest!!!

    5 of 5
    Dec 02, 2023
  • Dr Nah is extremely thorough; takes her time and genuinely builds a rapport.

    5 of 5
    Aug 02, 2023
  • Dr. Nah is wonderful. We appreciate her stellar dental skills, but without her kind, calm and gentle demeanor, who knows what we would get done.

    5 of 5
    Jun 29, 2023
  • Dr Nah listened carefully to our son's worries and took her time explaining what she was going to do and why even providing him with pictures. Seeing how concerned he was she even decided to do half of the 8 screws. Her kindness and compassion were exactly what our son needed to move forward. We are so grateful to her

    5 of 5
    Apr 29, 2023
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About the Patient Experience Rating System

The Patient Experience Rating is an average of all responses to the care provider related questions shown above from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question. Responses are measured on a scale of 1 to 5 with 5 being the best score. We are committed to true transparency. However, to ensure the comments are fair and correctly attributed, we review each one before posting to the website. We exclude entire comments that disclose patient’s protected health information, are off-topic, or include other confidential or inappropriate content. Comments will appear on provider bios only if providers have a minimum number of comments. Comments are shared internally for education purposes to ensure that we are doing our very best for the patients and families for whom we are privileged to care. The comments are submitted by patients and families and reflect their views and opinions. The comments are not endorsed by and do not reflect the views of Children’s Hospital of Philadelphia.

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