Sagori Mukhopadhyay, MD, MMSc
Areas of expertise: Neonatal-perinatal medicine
Locations: Main Building, CHOP at Penn Medicine Pennsylvania Hospital
About Sagori Mukhopadhyay, MD, MMSc
Titles
Attending Neonatologist
Associate Professor of Pediatrics, Perelman School of Medicine at the University of Pennsylvania
Certifications
Neonatal-Perinatal Medicine – American Board of Pediatrics
Pediatrics – American Board of Pediatrics
Awards and Honors
2014, Partners in Excellence Team Award, Brigham and Women’s Hospital
2012, Best Clinical Research Presentation, Section on Perinatal Pediatrics, American Academy of Pediatrics
2011, Farley Fund Award, Children’s Hospital Boston
2011, Von L. Meyer Traveling Award, Children’s Hospital Boston,
2010, Fredrick H. Lovejoy, Jr. Award for demonstrating clinical excellence, commitment to scholarship and compassion, Children’s Hospital Boston
2010, Schliesman Committee Travel Grant, Children’s Hospital Boston
2005, National-level Winner of Indian National Neonatology Quiz, National Neonatology Forum of India
2001, Kiriteswar Dutta Gold Medal in Medicine, Burdwan University, India
2001, Dr Subodh Mukhopadhyay Memorial Gold Medal in MBBS exam, Burdwan University, India
2001, Distinction in Surgery, Burdwan University, India
Leadership and Memberships
Memberships in Professional Organizations
International
2012-2013, Society of Pediatric Research Fellow
2005-present, Disaster Management group (IAP)
2004-present, Indian Academy of Pediatrics, IAP
National
2010-present, American Medical Association
2010-present, Perinatal Medicine Chapter (AAP)
2010-present, International Child Health Chapter (AAP)
2009-present, American Academy of Pediatrics, AAP
Editorial and Academic Positions
Editorial Positions
2013, Norwegian-Estonian Research Cooperation Program, Estonian Research Council, grant reviewer
2014-present, Archives of Disease in Childhood, ad hoc reviewer
2014-present, Pediatrics, ad hoc reviewer
2012-present, Pediatric Research, ad hoc reviewer
Academic and Institutional Committees
2015-present, Institutional Review Board, University of Pennsylvania, School of Medicine, member
2015-present, Study Section at Center for Pediatric Clinical Effectiveness, University of Pennsylvania, School of Medicine, reviewer
2014-present, Neonatal Nurse Practitioner Program, University of Pennsylvania, School of Medicine, lecturer and preceptor
Education & training
Medical Degree
MD - Burdwan Medical College and Hospital, Burdwan, India
Residency
Pediatrics - Sawai Man Singh Medical College and Hospital, India
Pediatrics - Boston Children’s Hospital, Boston, MA
Fellowship
Neonatal-Perinatal - Boston Children’s Hospital, Boston, MA
Additional Training
MMSc - Harvard Medical School and Harvard School of Public Health, Boston, MA
Publications
Publications
2022
Flannery DD, Mukhopadhyay S, Morales KH, Dhudasia MB, Passarella M, Gerber JS, Puopolo KM. Delivery Characteristics and the Risk of Early-Onset Neonatal Sepsis. Pediatrics. 2022;149(2):e2021052900. PubMed PMID: 35022750; PubMed Central PMCID: pending doi: 10.1542/peds.2021-052900. Online ahead of print.Flannery DD, Passarella M, Mukhopadhyay S, Dhudasia MB, Gerber JS, Lorch SA, Hennessy S, Puopolo KM. Early Childhood Antibiotic Utilization for Infants Discharged from the Neonatal Intensive Care Unit. J Perinatol. 2022. In press.
Mukhopadhyay S, Briker SM, Flannery DD, Dhudasia MB, Coggins SA, Woodford E, Walsh EM. Li S, Puopolo KM, Kuzniewicz MW. Time to Positivity of Blood Cultures in Neonatal Late-Onset Bacteremia. Arch Dis Child – Fetal Neonat Ed. Published Online First: 10 March 2022. doi: 10.1136/archdischild-2021-323416
Flannery DD, Zevallos Barboza A, Pfeifer MR, Hudak ML, Barnette K, Getzlaff TR, Ellington SR, Woodworth KR, Dhudasia MB, Mukhopadhyay S, Weinberg DD, Foglia EE, Puopolo KM. Perinatal COVID-19 maternal and neonatal outcomes at two academic birth hospitals. J Perinatol. 2022 Oct;42(10):1338-1345. doi: 10.1038/s41372-022-01446-x. Epub 2022 Jul 1. PMID: 35778485; PMCID: PMC9247898.
Triebwasser JE, Dhudasia MB, Mukhopadhyay S, Flannery DD, Gouma S, Hensley SE, Puopolo KM. Assessment of SARS-CoV-2 serostatus and hypertensive disorders of pregnancy. Am J Obstet Gynecol. 2022 Oct;227(4):664-666.e1. doi: 10.1016/j.ajog.2022.06.012. PubMed PMID: 35718110; PubMed Central PMCID: PMC9212257
Stefanovski D, Tapia IE, Lioy J, Sengupta S, Mukhopadhyay S, Corcoran A, Cornaglia MA, Cielo CM. Respiratory indices during sleep in healthy infants: A prospective longitudinal study and meta-analysis. Sleep Med. 2022 Nov;99:49-57. doi: 10.1016/j.sleep.2022.07.010. Epub 2022 Jul 31. PMID: 35963199.
Flannery DD, Gouma S, Dhudasia MB, Mukhopadhyay S, Pfeifer MR, Woodford EC, Briker SM, Triebwasser JE, Gerber JS, Morris JS, Weirick ME, McAllister CM, Hensley SE, Puopolo KM. Comparison of Maternal and Neonatal Antibody Levels After COVID-19 Vaccination vs SARS-CoV-2 Infection. JAMA Netw Open. 2022;5(11):e2240993. PubMed PMID: 36350652.f
Burris HH, Mullin AM, Dhudasia MB, Flannery DD, Mukhopadhyay S, Pfeifer MR, Woodford EC, Briker SM, Triebwasser JE, Morris JS, Montoya-Williams D, Gouma S, Hensley SE, Puopolo KM. Neighborhood Characteristics and Racial Disparities in Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Seropositivity in Pregnancy. Obstet Gynecol. 2022. In press.
Puopolo KM, Mukhopadhyay S, Hansen NI, Flannery DD, Greenberg RG, Sanchez PJ, Bell EF, DeMauro SB, Wyckoff MH, Eichenwald EC, Stoll BJ, for the Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network. Group B Streptococcal Infection in Extremely Preterm Neonates and Neurodevelopmental Outcomes at 2 Years. Clin Infect Dis. March 2022. PubMed PMID: pending; PubMed Central PMCID: pending. doi:10.1093/CID/CIAC222. Online ahead of print.2021
Flannery DD, Gouma S, Dhudasia MB, Mukhopadhyay S, Pfeifer MR, Woodford EC, Triebwasser JE, Gerber JS, Morris JS, Weirick ME, McAllister CM, Bolton MJ, Arevalo CP, Anderson EM, Goodwin EC, Hensley SE, Puopolo KM. Assessment of Maternal and Neonatal Cord Blood SARS-CoV-2 Antibodies and Placental Transfer Ratios. JAMA Pediatr. 2021 Jun 1;175(6):594-600. PubMed PMID: 33512440; PubMed Central PMCID: PMC7846944.
Flannery DD, Akinboyo IC, Mukhopadhyay S, Tribble AC, Song L, Chen F, Li Y, Gerber JS, Puopolo, KM. Antibiotic Susceptibility of Escherichia coli Among Infants Admitted to Neonatal Intensive Care Units Across the US from 2009 to 2017. JAMA Pediatr. 2021 Feb 1;175(2):168-175. PubMed PMID: 33165599; PubMed Central PMCID: PMC7653538.
Garber SJ, Dhudasia MB, Flannery DD, Passarella MR, Puopolo KM, Mukhopadhyay S. Delivery-based criteria for empiric antibiotic administration among preterm infants. J Perinatol. 2021 Feb;41(2):255-262. doi: 10.1038/s41372-020-00784-y. Epub 2020 Aug 13.PMID: 32792629 Free PMC article.
Mukhopadhyay S, Puopolo KM, Hansen NI, Lorch SA, DeMauro SB, Greenberg RG, Cotten CM, Sanchez PJ, Bell EF, Eichenwald EC, Stoll BJ; NICHD Neonatal Research Network. Arch Dis Child Fetal Neonatal Ed. Neurodevelopmental outcomes following neonatal late-onset sepsis and blood culture-negative conditions. 2021 Jan 21:fetalneonatal-2020-320664. doi: 10.1136/archdischild-2020-320664. Online ahead of print. PMID: 33478957.
2020
Mukhopadhyay S. Antibiotic stewardship in neonates and in neonatal intensive care units. Semin Perinatol. 2020 Dec;44(8):151321. doi: 10.1016/j.semperi.2020.151321. Epub 2020 Oct 13.PMID: 33158601
Rub DM, Dhudasia MB, Healy T, Mukhopadhyay S. Role of microbiological tests and biomarkers in antibiotic stewardship. Semin Perinatol. 2020 Dec;44(8):151328. doi: 10.1016/j.semperi.2020.151328. Epub 2020 Oct 12.PMID: 33158600
Underwood MA, Mukhopadhyay S, Lakshminrusimha S, Bevins CL. Neonatal intestinal dysbiosis. J Perinatol. 2020 Nov;40(11):1597-1608. doi: 10.1038/s41372-020-00829-2. Epub 2020 Sep 23.PMID: 32968220 Free PMC article.
Mukhopadhyay S, Wade KC, Dhudasia MB, Skerritt L, Chou JH, Dukhovny D, Puopolo KM. Clinical impact of neonatal hypoglycemia screening in the well-baby care. J Perinatol. 2020 Sep;40(9):1331-1338. doi: 10.1038/s41372-020-0641-1. Epub 2020 Mar 9.PMID: 32152490 Free PMC article.
Flannery DD, Gouma S, Dhudasia MB, Mukhopadhyay S, Pfeifer MR, Woodford EC, Gerber JS, Arevalo CP, Bolton MJ, Weirick ME, Goodwin EC, Anderson EM, Greenplate AR, Kim J, Han N, Pattekar A, Dougherty J, Kuthuru O, Mathew D, Baxter AE, Vella LA, Weaver J, Verma A, Leite R, Morris JS, Rader DJ, Elovitz MA, Wherry EJ, Puopolo KM, Hensley SE. SARS-CoV-2 seroprevalence among parturient women in Philadelphia. Sci Immunol. 2020 Jul 29;5(49):eabd5709. doi: 10.1126/sciimmunol.abd5709.PMID: 32727884 Free PMC article.
Flannery DD, Gouma S, Dhudasia MB, Mukhopadhyay S, Pfeifer MR, Woodford EC, Gerber JS, Arevalo CP, Bolton MJ, Weirick ME, Goodwin EC, Anderson EM, Greenplate AR, Kim J, Han N, Pattekar A, Dougherty J, Kuthuru O, Mathew D, Baxter AE, Vella LA, Weaver J, Verma A, Leite R, Morris JS, Rader DJ, Elovitz MA, Wherry EJ, Puopolo KM, Hensley SE. SARS-CoV-2 Seroprevalence Among Parturient Women. medRxiv. 2020 Jul 10:2020.07.08.20149179. doi: 10.1101/2020.07.08.20149179. Preprint.PMID: 32676623 Free PMC article. Updated.
Kuzniewicz MW, Mukhopadhyay S, Li S, Walsh EM, Puopolo KM. Time to Positivity of Neonatal Blood Cultures for Early-onset Sepsis. Pediatr Infect Dis J. 2020 Jul;39(7):634-640. doi: 10.1097/INF.0000000000002632.PMID: 32379197
Mukhopadhyay S, Puopolo KM, Hansen NI, Lorch SA, DeMauro SB, Greenberg RG, Cotten CM, Sánchez PJ, Bell EF, Eichenwald EC, Stoll BJ; Impact of Early-Onset Sepsis and Antibiotic Use on Death or Survival with Neurodevelopmental Impairment at 2 Years of Age among Extremely Preterm Infants. Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network. J Pediatr. 2020 Jun;221:39-46.e5. doi: 10.1016/j.jpeds.2020.02.038. PMID: 32446491 [PubMed - in process]
Flannery DD, Mukhopadhyay S, Jensen EA, Gerber JS, Passarella MR, Dysart K, Aghai ZH, Greenspan J, Puopolo KM. Influence of Patient Characteristics on Antibiotic Use Rates Among Preterm Infants. J Pediatric Infect Dis Soc. 2020 Mar 14. pii: piaa022. doi: 10.1093/jpids/piaa022. [Epub ahead of print]. PMID: 32170951
2019
Mukhopadhyay S, Puopolo KM. Preventing Neonatal Group B Streptococcus Disease: The Limits of Success. JAMA Pediatr. 2019 Jan 14. doi: 10.1001/jamapediatrics.2018.4824. [Epub ahead of print] PMID: 30640370
Greenberg RG, Chowdhury D, Hansen NI, Smith PB, Stoll BJ, Mukhopadhyay S, Higgins RD, Cotten CM; Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network et al. Prolonged duration of early antibiotic therapy in extremely premature infants. Pediatr Res. 2019 Jan 22. doi: 10.1038/s41390-019-0300-4. [Epub ahead of print]. PMID: 30737489
2018
Flannery DD, Ross RK, Mukhopadhyay S, Tribble AC, Puopolo KM, Gerber JS. Temporal Trends and Center Variation in Early Antibiotic Use Among Premature Infants. JAMA Network Open. 2018;1(1):e180164.
Mukhopadhyay S, Sengupta S, Puopolo KM. Challenges and opportunities for antibiotic stewardship among preterm infants. Arch Dis Child Fetal Neonatal Ed. 2018 Nov 13. pii: fetalneonatal-2018-315412. doi: 10.1136/archdischild-2018-315412. [Epub ahead of print] Review. PMID: 30425110
2015
Mukhopadhyay S, Riley L, Puopolo K, Lieberman E, Johnson Lise. Effect of early-onset sepsis evaluations on in-hospital breastfeeding practices among asymptomatic term neonates. Hosp Pediatr. 2015 Apr;5(4):203-10. PMID: 25832975.
Mukhopadhyay S, Puopolo K. Neonatal Early-Onset Sepsis: Epidemiology and Risk Assessment. NeoReviews Vol. 16 No. 4 April 1, 2015. pp. e221 -e230.
2014
Little SE, Robinson NJ, Puopolo KM, Mukhopadhyay S, Wilkins-Haug LE, Acker DA, Zera CA. The effect of obstetric practice change to reduce early term delivery on perinatal outcome. J Perinatol. 2014 Jan. doi: 10.1038/jp.2013.166. [Epub ahead of print]; PMID:24406741.
Mukhopadhyay S, Dukhovny D, Mao W, Eichenwald E, Puopolo K. 2010 Perinatal GBS Prevention Guideline and Resource Utilization. Pediatrics. 2014 Feb;133(2):196-203; PMID:24446442.
Abstracts (includes Posters and Scientific Presentations)
2013
Mukhopadhyay S, Puopolo K. Impact of Transcutaneous carbon dioxide monitoring on frequency of neonatal blood gas measurements. Translational Science, Washington DC, 2013 and; Poster Symposium, Childrens Hospital Boston, Boston, 2013 and; Translational Science 2013 Abstracts. Clinical and Translational Science, 6: 103–164. doi: 10.1111/cts.12047.
Lectures by Invitation
2014
Mukhopadhyay S. Risk Based Sepsis Evaluations: Balancing Prevention with Intervention. Brigham and Women’s Newborn Medicine Grand Rounds. Brigham and Women’s Hospital, Boston, MA; Newborn Epidemiology & Clinical Research Seminar Series. Beth Israel Deaconess Medical Center, Boston MA.
Mukhopadhyay S, Gupta M, Puopolo K. Management of Infants at Risk for Early-Onset Sepsis: Practice Variation in Massachusetts. Platform presentation. Neonatal Quality Improvement Collaborative Meeting (neoQIC), Boston, MA.
2013
Mukhopadhyay S, Dukhovny D, Eichenwald E, Puopolo K. Neonatal Sepsis Risk Calculator: Projected Impact on a Retrospective Cohort. Platform presentation at Pediatric Academic Society Conference, Washington DC; New England Perinatal Society Conference, Newport, MA.
Books
Mukhopadhyay S, Laskmanan A, Ghanta S, Sajti E, Leeman K, Litt J, Sparger K. In: Neonatology Review: Q&A. 2nd Edition. Brodsky D, Martin C, editors. Lulu publications, 2014.
Editorials, Reviews, Chapters
2009
Mukhopadhyay S, Skotko B, Berry G. Metabolism. In: Boston Combined Residency Program Pediatric Guidebook [Handbook]. Eds Ruebner R. Ed. Boston, 3rd Edition. 2009.
Mukhopadhyay S, Agarwal R, Paul V. Care of low birth weight babies. In: Dr Ghai’s Essentials of Pediatrics [Textbook] Paul VK, Bagga A, eds. CBS publishers & distributors, New Delhi, 7th edition, 2009.
Deorari AK, Sivanandan S, Mukhopadhyay S, Agarwal R. Thermal Protection. In: Dr Ghai’s Essentials of Pediatrics [Textbook] Paul VK, Bagga A, eds. CBS publishers & distributors, New Delhi, 7th edition, 2009.
Mukhopadhyay S, Agarwal R, Paul V. Care at birth and during first few weeks of life. In: Dr Ghai’s Essentials of Pediatrics [Textbook] Paul VK, Bagga A, eds. CBS publishers & distributors, New Delhi, 7th edition, 2009.
2008
Mukhopadhyay S, Purohit A. ‘Milroy’s Disease’. In: Verma A, editor. Spotters in Pediatrics [Atlas] Jaypee brothers medical, 2008.