Brad Lindell, MD, FAAP

Dr. Lindell is a graduate of the University of Georgia and Vanderbilt University School of Medicine. He completed his pediatrics residency training and pediatric critical care fellowship at Children's Hospital of Philadelphia, where he also served as a chief resident. He is currently an Assistant Professor of Anesthesiology and Critical Care and Pediatrics at the Perelman School of Medicine at the University of Pennsylvania and an attending physician in the pediatric intensive care unit at Children's Hospital of Philadelphia.

Dr. Lindell’s patient-oriented research program is focused on designing precision approaches to immunomodulation in critically ill children. Pediatric sepsis is a leading cause of death of hospitalized children worldwide. While sepsis is defined as life-threatening organ dysfunction that develops in the setting of immune dysregulation, optimal management of immune dysregulation in pediatric sepsis is a fundamental knowledge gap. A successful precision medicine approach to pediatric sepsis requires that we understand the molecular events that cause organ failure, which of these events are potentially reversible, and how to identify this reversible patient pathobiology in real-time. To address this gap, Dr. Lindell’s NIH-funded research focuses on identifying targetable mechanisms of immune dysregulation in pediatric patients with sepsis and ex vivo testing of candidate therapeutics in cell culture.