M. Anna Kowalska, PhD
Locations: Main Building
About M. Anna Kowalska, PhD
Titles
Senior Scientist
Awards and Honors
2009-201, Grant-in-Aid from American Heart Association “Platelet Factor 4 in Thrombosis: Intersection of Physiology and Pathology”
2007-2009, Grant-in-Aid from American Heart Association “The role of platelet-specific chemokines in inflammation”
2002-2005, Grant-in-Aid from American Heart Association “Defining the biology of PF4”
Leadership and Memberships
Memberships in Professional Organizations
American Society of Hematology
American Heart Association
International Society on Thrombosis and Haemostasis
Editorial and Academic Positions
Editorial Positions
Reviewer
Blood
Journal of Thrombosis and Haemostasis
Thrombosis and Haemostasis
Education & training
Undergraduate Degree
BS in Physics - University of Lodz, Lodz, Poland
Graduate Degree
PhD in Biochemistry - University of Lodz, Lodz, Poland
MS in Biophysics - University of Lodz, Lodz, Poland
Fellowship
Postdoctoral Fellow - Thrombosis Research Center, Temple University School of Medicine, Philadelphia, PA
Publications
Publications
2016
Stasiak M, Boncela J, Perreau C, Karamanou K, Chatron-Colliet A, Proult I, Przygodzka P, Chakravarti S, Maquart F-X, Kowalska MA, Wegrowski Y and Brézillon S. Lumican inhibits SNAIL-induced melanoma cell migration specifically by blocking MMP-14 activity. PLOS One March 1 2016. PLoS One 11(3):e0150226. doi: 10.1371/journal.pone.0150226, 2016.
Fuentes RE, Zaitsev S, Ahn HS, Hayes V, Kowalska M, Lambert MP, Wang Y, Siegel DL, Bougie DW, Aster RH, Myers DD, Stepanova V, Cines DB, Muzykantov VR, Poncz M. A chimeric platelet-targeted urokinase prodrug selectively blocks new thrombus formation.
J Clin Invest. 126(2):483-94, 2016.
2015
Lambert MP, Meng R, Xiao L, Harper DC, Marks MS, Kowalska MA, Poncz M. Intramedullary megakaryocytes internalize released platelet factor 4 and store it in alpha granules. J Thromb Haemost. 13:1888-99. 2015.
Meng R, Wu J, Harper DC, Wang Y, Kowalska MA, Abrams CS, Brass LF, Poncz M, Stalker TJ, Marks MS. Defective release of alpha granule and lysosome contents from platelets in mouse Hermasky-Pudlak syndrome models. Blood 125:1623-32, 2015..
2014
Skewis LR, Lebedeva T, Papkov V, Thayer EC, Massefski W, Cuker A, Nagaswami C, Litvinov RI, Kowalska MA, Rauova L, Poncz M, Weisel JW, Lowery TJ, Cines DB.,T2 Magnetic Resonance: A Diagnostic Platform for Studying Integrated Hemostasis in Whole Blood—Proof of Concept. Clinical Chemistry. 60: 1174-82, 2014 .
Shi G, Field DJ, Ko K, Ture S, Srivastava K, Levy S, Kowalska MA, Poncz M, Fowell DJ, and Morrell CN. Platelet factor 4 limits Th17 differentiation and cardiac allograft rejection. J Clin Invest. 124: 543-552, 2014.
Kowalska MA, Zhao G, Zhai L, David G, Krishnaswamy S, Poncz M. Modulation of protein C activation by histones, platelet factor 4 and heparinoids: New insights into activated protein C formation. Arterioscler Thromb Vasc Biol. 34:120-126, 2014.
Lectures by Invitation
2016
Kowalska MA. Seminar at the University of Reims, Champagne Ardenne, Laboratoire de Biochimie Médicale et de Biologie Moléculaire; 2016 May; Reims, France.
Editorials, Reviews, Chapters
Fukami MH, Holmsen H, Kowalska MA, Niewiarowski S: Platelet Secretion. Chapter 32. In Haemostasis and Thrombosis: Basic principles and Clinical Practice. 4th edition. Edited by RW. Colman, J. Hirsh, VJ Marder, AW Clowes, JN George. Lippincott Williams & Wilkins, 2000.