David A. Hill, MD, PhD, FAAP
Areas of expertise: Food allergy, Eosinophilic esophagitis, Severe allergy/anaphylaxis
Locations: Main Building, Buerger Center for Advanced Pediatric Care
About David A. Hill, MD, PhD, FAAP
David A. Hill, MD, PhD, FAAP, is a board-certified pediatric allergist, immunologist, and attending physician at Children’s Hospital of Philadelphia (CHOP). He is also an assistant professor of pediatrics at the University of Pennsylvania Perelman School of Medicine. Dr. Hill specializes in diagnosing and treating children with food allergies and asthma, and he is actively researching new diagnostic tools and cutting-edge treatments for children with these conditions.
Dr. Hill became a pediatrician and chose clinical allergy as his specialty because he feels that every child should have the opportunity to live a happy and healthy life – free from the cares and consequences of chronic disease. He strives to achieve this goal through direct pediatric patient care and his research program, as well as his academic and medical leadership roles.
Education and experience
Dr. Hill earned his bachelor’s degree from Carnegie Mellon University in Pittsburgh, PA, and his medical degree and Doctor of Philosophy from the Perelman School of Medicine at the University of Pennsylvania (Penn). He completed his pediatric residency training at CHOP, then served a 2-year term as a clinical fellow in the hospital’s Division of Allergy and Immunology.
After his intensive training, Dr. Hill accepted an instructorship at Penn and CHOP while he completed his post-doctoral research. He was promoted to assistant professor at Penn and attending physician at CHOP in 2019. Since then, Dr. Hill has continued his research as a principal investigator. The Hill Lab studies how diet and metabolism influence patients’ immune health and frequency of inflammatory disease.
Dr. Hill is actively involved in numerous professional and scientific societies including the American Academy of Pediatrics and the American Academy of Allergy, Asthma and Immunology. He has published more than a hundred scientific papers, reviews and abstracts, presented at regional, national, and international meetings, and received several awards for the impact of his work.
Research
In addition to his clinical work, Dr. Hill oversees a team of researchers at CHOP and Penn. The Hill Lab studies how diet and metabolism influence immune health and inflammatory disease. The team has more than 10 ongoing studies that range from investigations of the fundamental mechanism of disease to clinical trials. Under Dr. Hill's direction, physicians and scientists are working together to translate discoveries in the laboratory into improved patient care for children at the bedside.
Titles
Attending Physician
Assistant Professor of Pediatrics, Perelman School of Medicine at the University of Pennsylvania
Certifications
Allergy and Immunology – American Board of Allergy and Immunology
Pediatrics – American Board of Pediatrics
Awards and Honors
2023, AAAAI Faculty Development Award
2023, Outstanding Reviewer Award, The Journal of Allergy and Clinical Immunology
2022, Hartwell Individual Biomedical Research Award
2022, Fellow, The College of Physicians of Philadelphia
2022, Fellow, The College of Allergy, Asthma & Immunology
2022, Fellow, The American Academy of Allergy, Asthma & Immunology
2021, Young Physician-Scientist Award, American Society for Clinical Investigation
2020, Fellow, the American Academy of Pediatrics
2020, Hope Research Award, AAAAI/APFED
2019, Young Faculty Award, American College of Allergy, Asthma & Immunology (ACAAI)
2019, Distinguished Research Trainee Award, CHOP
2017, Clemens Von Pirquet Award, ACAAI
2016, Clemens Von Pirquet Award, ACAAI
2016, Senior Resident Research Award, CHOP
2014, Chrysalis Award, American Academy of Allergy, Asthma & Immunology (AAAAI)
2013, Henrietta and Jacob Lowenburg Prize in Pediatrics, Perelman SOM
2012, Saul Winegrad Outstanding Dissertation Award, Perelman SOM
2011, Mary Ellis Bell Prize for Medical Research, Perelman SOM
2005, Andrew Carnegie Society Scholar, Carnegie Mellon University
Leadership and Memberships
Memberships in Professional Organizations
Societies
International
2017-present, Member, World Allergy Organization
National
2016-2024, Member/Fellow, American College of Allergy, Asthma, and Immunology (ACAAI)
-Committees: Asthma (2017-2019); Food Allergy (2019-2021)
2016-Present, Member/Fellow, American Academy of Allergy, Asthma, and Immunology (AAAAI)
-Committees: Allergic Inflammation (2017-2027); Eos. GI Disorders. (2017-2027)
2013-Present, Member/Fellow, American Academy of Pediatrics (AAP)
-Sections: Allergy and Immunology (2018-present)
Local/Regional
2022 – Present Fellow, The College of Physicians of Philadelphia
2019 – 2024 Member, Eastern Society for Pediatric Research (ESPR)
Scientific Committees
National
2021-2024, NIH Early Career Reviewer program
2025-Present, Reviewer, Special Emphasis Panel/Scientific Review Group 2025/05 IMHA
Editorial and Academic Positions
Editorial Positions
2022-present, The Journal of Allergy and Clinical Immunology, Editorial Board
2018-2022, Associate Editor, BMC Pediatrics
Ad Hoc Reviewer
Cell Metabolism
The Journal of Allergy and Clinical Immunology
Genes and Development
Proceedings of the National Academy of Sciences of the United States of America
The Journal of Allergy and Clinical Immunology: In Practice
Cell Reports
Clinical and Translational Medicine
JCI Insight
Frontiers in Immunology
Pediatrics
Academic and Institutional Committees
2023-present, Penn Perelman SOM Immunology Graduate Group Admissions Committee
2023-present, Department of Pediatrics Research Council
2022-present, Research Institute Workforce Diversity Working Group
2021-2022, Research Symposium Planning Committee
2021, Blavatnik Family Fellowship Selection Committee, Perelman School of Medicine
2020, Research Paper Prize Committee, Perelman School of Medicine
2019-2020, Allergy and Immunology Fellowship Admissions Committee
2019-present, MSTP Admissions Committee, Perelman School of Medicine
2019-present, Office of Faculty Development Advisory Committee
2019-present, Biorepository Core Operational Committee
2005-present, Carnegie Mellon University Admission Counsel
Research Interests
Food allergy, Allergic march, Transcriptional regulation of innate immune cells, Obesity-associated immune dysfunction
Education & training
Graduate Degree
PhD - University of Pennsylvania, Philadelphia PA
Medical Degree
MD - University of Pennsylvania, Philadelphia PA
Internship
Pediatrics - Children’s Hospital of Philadelphia, Philadelphia, PA
Residency
Pediatrics - Children’s Hospital of Philadelphia, Philadelphia, PA
Fellowship
Pediatric Allergy and Immunology - Children’s Hospital of Philadelphia, Philadelphia, PA
Post-Doctoral Research Fellow - Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA
Publications
Publications
2024
Seshadri N, Faig W, Young LR, Hill DA. Risk factors for hospitalization in subspecialty patients with severe persistent asthma. Respir Med. 2024 Dec;235:107867. doi: 10.1016/j.rmed.2024.107867. Epub 2024 Nov 16. PubMed PMID: 39551249; PubMed Central PMCID: PMC11634629.
Wright BL, Abonia JP, Abud EM, Aceves SS, Ackerman SJ, Braskett M, Chang JW, Chehade M, Constantine GM, Davis CM, Dellon ES, Doyle AD, Durban R, Hill DA, Jensen ET, Kewalramani A, Khoury P, Klion AD, Kottyan L, Kuang FL, McGowan EC, Ruffner MA, Spencer LA, Spergel JM, Uchida AM, Wechsler JB, Pesek RD. Advances and ongoing challenges in eosinophilic gastrointestinal disorders presented at the CEGIR/TIGERs Symposium at the 2024 American Academy of Allergy, Asthma & Immunology meeting. J Allergy Clin Immunol. 2024 Oct;154(4):882-892. doi: 10.1016/j.jaci.2024.07.022. Epub 2024 Aug 5. Review. PubMed PMID: 39111348; PubMed Central PMCID: PMC11456379.
Paneru BD, Chini J, McCright SJ, DeMarco N, Miller J, Joannas LD, Henao-Mejia J, Titchenell PM, Merrick DM, Lim HW, Lazar MA, Hill DA. Myeloid-derived miR-6236 potentiates adipocyte insulin signaling and prevents hyperglycemia during obesity. Nat Commun. 2024 Jun 25;15(1):5394. doi: 10.1038/s41467-024-49632-z. PubMed PMID: 38918428; PubMed Central PMCID: PMC11199588.
Senter JP, Aisenberg LK, Dudley JW, Luan X, Huang J, Kenyon CC, Hill DA. COVID-19 and Asthma Onset in Children. Pediatrics. 2024 May 1;153(5). doi: 10.1542/peds.2023-064615. PubMed PMID: 38606487; PubMed Central PMCID: PMC11035159.
2023
Chehade M, Wright BL, Atkins D, Aceves SS, Ackerman SJ, Assa'ad AH, Bauer M, Collins MH, Commins SP, Davis CM, Dellon ES, Doerfler B, Gleich GJ, Gupta SK, Hill DA, Jensen ET, Katzka D, Kliewer K, Kodroff E, Kottyan LC, Kyle S, Muir AB, Pesek RD, Peterson K, Shreffler WG, Spergel JM, Strobel MJ, Wechsler J, Zimmermann N, Furuta GT, Rothenberg ME. Breakthroughs in understanding and treating eosinophilic gastrointestinal diseases presented at the CEGIR/TIGERs Symposium at the 2022 American Academy of Allergy, Asthma & Immunology Meeting. J Allergy Clin Immunol. 2023 Dec;152(6):1382-1393. doi: 10.1016/j.jaci.2023.08.021. Epub 2023 Sep 3. Review. PubMed PMID: 37660987.
Hill DA, Muir AB. The immune-epithelial interface in eosinophilic esophagitis: a conversation. Front Allergy. 2023;4:1270581. doi: 10.3389/falgy.2023.1270581. eCollection 2023. PubMed PMID: 37854541; PubMed Central PMCID: PMC10579787.
Gabryszewski SJ, Dudley J, Shu D, Faerber JA, Grundmeier RW, Fiks AG, Hill DA. Patterns in the Development of Pediatric Allergy. Pediatrics. 2023 Aug 1;152(2). doi: 10.1542/peds.2022-060531. PubMed PMID: 37489286; PubMed Central PMCID: PMC10389774.
Paneru BD, Hill DA. The role of extracellular vesicle-derived miRNAs in adipose tissue function and metabolic health. Immunometabolism (Cobham). 2023 Jul;5(3):e00027. doi: 10.1097/IN9.0000000000000027. eCollection 2023 Jul. Review. PubMed PMID: 37501663; PubMed Central PMCID: PMC10371064.
Xiao Y, Batmanov K, Hu W, Zhu K, Tom AY, Guan D, Jiang C, Cheng L, McCright SJ, Yang EC, Lanza MR, Liu Y, Hill DA, Lazar MA. Hepatocytes demarcated by EphB2 contribute to the progression of nonalcoholic steatohepatitis. Sci Transl Med. 2023 Feb 8;15(682):eadc9653. doi: 10.1126/scitranslmed.adc9653. Epub 2023 Feb 8. PubMed PMID: 36753562; PubMed Central PMCID: PMC10234568.
2022
Sayed S, Diwadkar AR, Dudley JW, O’Brien J, Dvorin D, Kenyon CK, Himes BE, Hill DA*, Henrickson SE. COVID-19 Pandemic-Related Reductions in Pediatric Asthma Exacerbations Corresponded with an Overall Decrease in Respiratory Viral Infections. Journal of Allergy and Clinical Immunology: In Practice. 2022 Jan;10(1)91-99. PMID: 34785388. PMCID: PMC8590625.
Spergel BS, Ruffner MA, Godwin B, Liacouras CA, Cianferoni A, Gober L, Hill DA, Brown-Whitehorn TA, Chaiboonma K, Aceves SA, Muir AM, Spergel JM. Improvement in Eosinophilic Esophagitis when using Dupilumab for other Indications or Compassionate Use. Annals of Allergy, Asthma, and Immunology. 2022 Jan 25;S1081-1206(22)00020-5. PMID: 35085819. PMCID: Pending.
Sterling JK, Baumann B, Foshe S, Voigt A, Guttha S, Alnemri A, McCright SJ, Li M, Zauhar RJ, Montezuma SR, Kapphahn RJ, Chavali VRM, Hill DA, Ferrington DA, Stambolian D, Mullins RF, Merrick D, and Dunaief JL. Inflammatory adipose activates a nutritional immunity pathway leading to retinal dysfunction. Cell Reports. 2022 Jun 14;39(11):110942. PMID: 35705048. PMCID: PMC9248858.
Vakili S, Paneru B, Guerrier CM, Miller J, Baumrin E, Forrestel A, Lynn K, Frank I, Lo Re V, Collman RG, Hill DA*. Altered adipose tissue macrophage populations in people with HIV on integrase inhibitor-containing ART. AIDS. 2022 Sep 1;36(11):1493-1500. PMID: 35848549. PMCID: PMC9391287.
2021
Gabryszewski SJ, Chang X, Dudley JW, Mentch F, March M, Holmes JH, Moore J, Grundmeier RW, Hakonarson H, Hill DA*. Unsupervised modeling and genome-wide association identify novel features of allergic march trajectories. Journal of Allergy and Clinical Immunology. 2021 Feb;147(2):677-685. PMID: 32650023. PMCID: PMC7790850.
Ruffner MA, Hu A, Dilollo J, Benocek K, Shows D, Gluck M, Spergel JM, Ziegler SF, Hill DA*, Cerosaletti K. Conserved interferon signature between adult and pediatric eosinophilic esophagitis. Journal of Immunology. 2021 Mar 15;206(6):1361-1371. PMID: 33558373. PMCID: PMC7946729.
Floyd GC, Dudley JW, Xiao R, Feudtner C, Taquechel K, Miller K, Henrickson SE, Hill DA, Kenyon CK. Prevalence of asthma in hospitalized and non-hospitalized children with COVID-19. Journal of Allergy and Clinical Immunology: In Practice. 2021 May;(9)5:2077-2079. PMID: 33676051. PMCID: PMC7927636.
Gabryszewski SJ, Dudley JW, Grundmeier RW, Hill DA*. Early-life environmental exposures associate with individual and cumulative allergic morbidity. Pediatric Allergy and Immunology. 2021 Jul;32(5):1089-1093. PMID: 33616233. PMCID: PMC8249342.
Dilollo J, Rodríguez-López EM, Wilkey L, Martin EK, Spergel JM, Hill DA*. Peripheral markers of allergen-specific immune activation predict clinical allergy in eosinophilic esophagitis. Allergy. 2021 Nov;76(11):3470-3478. PMID: 33840099. PMCID: PMC8502783.
2020
Kenyon CK, Hill DA, Henrickson SE, Bryant-Stephens TC, Zorc JJ. Initial effects of the COVID-19 pandemic on pediatric asthma emergency department utilization. Journal of Allergy and Clinical Immunology: In Practice. 2020 Sep;8(8):2774-2776.e1. PMID: 32522565. PMCID: PMC7483361.
Ruffner MA, Wang KY, Dudley JW, Cianferoni A, Grundmeier RW, Spergel JM, Brown-Whitehorn TF, Hill DA*. Elevated atopic comorbidity in patients with food protein-induced enterocolitis. Journal of Allergy and Clinical Immunology: In Practice. 2020 Mar; 8(3):1039-1046. PMID: 31759160. PMCID: PMC7064432.
2019
Bosticardo M, Yamazaki Y, Cowan J, Giardino G, Corsino C, Scalia G, Prencipe R, Ruffner M, Hill DA, Sakovich I, Yemialyanavaa I, Tam JS, Padem N, Elder ME, Sleasman JW, Perez E, Niebur H, Seroogy CM, Sharapova S, Gebbia J, Kleiner GI, Peake J, Abbott J, Gelfand E, Crestani E, Biggs C, Butte M, Hartog N, Hayward A, Chen K, Heimall J, Seeborg F, Bartnikas LM, Cooper MA, Pignata C, Bhandoola A, Notarangelo LD. Heterozygous FOXN1 variants cause low TRECs and severe T cell lymphopenia, revealing a crucial role of FOXN1 in supporting thymopoiesis early in life. The American Journal of Human Genetics. 2019 Sep 5;105(3):549-561. PMID: 31447097. PMCID: PMC6731368.
Jaitin DA, Adlung L, Thaiss CA, Weiner A, Li B, Descamps H, Lundgren P, Bleriot C, Liu Z, Deczkowska A, Keren-Shaul H, David E, Zmora N, Eldar SM, Lubezky N, Shibolet O, Hill DA, Lazar MA, Colonna M, Ginhoux F, Shapiro H, Elinav E, Amit I. Lipid-associated macrophages control metabolic homeostasis in a Trem2-dependent manner. Cell. 2019 Jul 25; 178(3):686-698. PMID: 31257031. PMCID: PMC7068689.
2018
Hill DA, Spergel JM. Epithelial acid imbalance in eosinophilic esophagitis. J Allergy Clin Immunol. 2018 Oct 10. pii: S0091-6749(18)31435-0. doi: 10.1016/j.jaci.2018.09.026. [Epub ahead of print]
Hill DA, Grundmeier RW, Ramos M, Spergel JM. Eosinophilic Esophagitis Is a Late Manifestation of the Allergic March. J Allergy Clin Immunol Pract. 2018 Sep - Oct;6(5):1528-1533. doi: 10.1016/j.jaip.2018.05.010. Epub 2018 Jun 25.
Nelson VL, Nguyen HCB, Garcìa-Cañaveras JC, Briggs ER, Ho WY, DiSpirito JR, Marinis JM, Hill DA, Lazar MA. PPARγ is a nexus controlling alternative activation of macrophages via glutamine metabolism. Genes Dev. 2018 Aug 1;32(15-16):1035-1044. doi: 10.1101/gad.312355.118. Epub 2018 Jul 13.
Hill DA, Camargo CA Jr, Paller AS, Spergel JM. A march by any other name. Ann Allergy Asthma Immunol. 2018 Jul;121(1):137-138. doi: 10.1016/j.anai.2018.04.014.
Nelson VL, Nguyen HCB, Garcìa-Cañaveras JC, Briggs ER, Ho WY, DiSpirito JR, Marinis JM, Hill DA, Lazar MA. PPAR is a nexus controlling alternative activation of macrophages via glutamine metabolism. Genes and Development. 2018. Jul 13. PMID: 30006480.
Hill DA*, Grundmeier RW, Ramos M, Spergel JM. Eosinophilic esophagitis is a late manifestation of the allergic march. Journal of Allergy and Clinical Immunology: In Practice. 2018. Jun 13. PMID: 29954692.
Hill DA, Lim HW, Kim YH, Ho WY, Foong YH, Nelson VL, Nguyen HCB, Chegireddy K, Kim J, Habertheuer A, Vallabhajosyula P, Kambayashi T, Won KJ, Lazar MA. Distinct macrophage populations direct inflammatory versus physiological changes in adipose tissue. Proceedings of the National Academy of Sciences USA. 2018 May 29; 115(22):E5096-E5105. PMID: 29760084. PMCID: PMC5984532.
Raje N, Snyder BL, Hill DA, Streicher JL, Sullivan KE. Severe immunodeficiency associated with acute lymphoblastic leukemia and its treatment. Annals of Allergy, Asthma and Immunology. 2018 May; 120(5):537-538. PMID: 29563054. PMCID: PMC5975371.
Hill DA, Spergel JM. The atopic march: Critical evidence and clinical relevance. Ann Allergy Asthma Immunol. 2018 Feb;120(2):131-137. doi: 10.1016/j.anai.2017.10.037.
Hill DA, Spergel JM. Is eosinophilic esophagitis a member of the atopic march? Ann Allergy Asthma Immunol. 2018 Feb;120(2):113-114. doi: 10.1016/j.anai.2017.10.003.
Hill DA*, Barz Leahy A, Sciasci J, O’Neill SP, Reilly A, Balamuth N, Seeholzer SH, Spergel JM, Brown-Whitehorn TF. Medication contaminants as a potential cause of anaphylaxis to vincristine. Pediatric Blood and Cancer. 2018 Jan;65(1). PMID: 28834048. PMCID: PMC5978699.
2017
Hill DA, Dudley JW, Spergel JM. The prevalence of eosinophilic esophagitis in pediatric patients with IgE-mediated food allergy. Journal of Allergy and Clinical Immunology: In Practice. 2017 Mar-Apr;5(2):369-375. PMID: 28042003. PMCID: PMC5346349.
2016
Papazyan R, Sun Z, Hoon Kim Y, Titchenell PM, Hill DA, Lu W, Damle M, Wan M, Zhang Y, Briggs ER, Rabinowitz JD, Lazar MA. Physiological Suppression of Lipotoxic Liver Damage by Complementary Actions of HDAC3 and SCAP/SREBP. Cell Metabolism. 2016 Dec 13;24(6):863-874. PMID: 27866836. PMCID: PMC5159233.
Hill DA*, Grundmeier RW, Ram G, Spergel JM. The epidemiologic characteristics of healthcare provider-diagnosed eczema, asthma, allergic rhinitis, and food allergy in children: a retrospective cohort study. BMC Pediatrics. 2016 Aug 20;16:133. PMID: 27542726. PMCID: PMC4992234.
Hill DA, Spergel JM. The Immunologic Mechanisms of Eosinophilic Esophagitis. Curr Allergy Asthma Rep. 2016 Feb;16(2):9. doi: 10.1007/s11882-015-0592-3.
2015
Hill DA*, Shuker M, Cianferoni A, Wong T, Ruchelli E, Spergel JM, Brown-Whitehorn TF. The development of IgE-mediated immediate hypersensitivity after the diagnosis of eosinophilic esophagitis to the same food. Journal of Allergy and Clinical Immunology: In Practice. 2015 Jan-Feb;3(1):123-4. PMID: 25577634. PMCID: PMC5598762.
2014
Hill DA, Siracusa MD, Ruymann KR, Tait Wojno ED, Artis D, Spergel JM. Omalizumab therapy is associated with reduced circulating basophil populations in asthmatic children. Allergy. 2014 May;69(5):674-7. PMID: 24611974. PMCID: PMC3981884.
Maggadottir SM, Hill DA, Ruymann KR, Brown-Whitehorn TF, Cianferoni A, Shuker M, Wang ML, Chikwava K, Verma R, Liacouras CA, Spergel JM. Resolution of acute IgE-mediated allergy with development of eosinophilic esophagitis triggered by the same food. Journal of Allergy and Clinical Immunology. 2014 May;133(5):1487-9. PMID: 24636092.
2013
Noti M, Wojno ED, Kim BS, Siracusa MC, Giacomin PR, Nair MG, Benitez AJ, Ruymann KR, Muir AB, Hill DA, Chikwava KR, Moghaddam AE, Sattentau QJ, Alex A, Zhou C, Yearley JH, Menard-Katcher P, Kubo M, Obata-Ninomiya K, Karasuyama H, Comeau MR, Brown-Whitehorn T, de Waal Malefyt R, Sleiman PM, Hakonarson H, Cianferoni A, Falk GW, Wang ML, Spergel JM, Artis D. Thymic stromal lymphopoietin-elicited basophil responses promote eosinophilic esophagitis. Nature Medicine. 2013 Aug;19(8):1005-13. PMID: 23872715. PMCID: PMC3951204.
Hill DA, Artis D. The influence of commensal bacteria-derived signals on basophil-associated allergic inflammation. Gut Microbes. 2013 Jan-Feb;4(1):76-83. doi: 10.4161/gmic.22759. Epub 2012 Nov 8.
2012
Carvalho LP, Petritus P, Trochtenberg A, Hill DA, Artis D, Scott P. Leishmania major induced lymph node hypertrophy is dependent upon TLR9. Journal of Immunology. 2012 Aug;188(3):1394-401. PMID: 22205030. PMCID: PMC3262876.
Dollive S, Peterfreund G, Sherrill-Mix S, Bittinger K, Sinha R, Nabel C, Hill DA, Artis D, Bachman M, Custers-Allen R, Grunberg S, Wu G, Lewis J, Bushman FD. A tool kit for quantifying eukaryotic rRNA gene sequences from human microbiome samples. Genome Biology. 2012 Jul;13(7):R60. PMID: 22759449. PMCID: PMC4053730.
Hill DA, Siracusa MC, Abt MC, Kim BK, Kobuley D, Kubo M, Kambayashi T, LaRosa DF, Renner ED, Orange JS, Bushman FD, Artis D. Commensal bacteria-derived signals regulate basophil hematopoiesis and allergic inflammation. Nature Medicine. 2012 Mar;18(4):538-46. PMID: 22447074. PMCID: PMC3321082. Cited >300 times.
Carvalho LP, Petritus PM, Trochtenberg AL, Zaph C, Hill DA, Artis D, Scott P. Lymph node hypertrophy following Leishmania major infection is dependent on TLR9. J Immunol. 2012 Feb 1;188(3):1394-401. doi: 10.4049/jimmunol.1101018. Epub 2011 Dec 28.
2011
Siracusa MC, Saenz SA, Hill DA, Kim BS, Headley MB, Doering TA, Wherry EJ, Jessup HK, Siegel LA, Kambayashi T, Dudek EC, Kubo M, Cianferoni A, Spergel JM, Ziegler SF, Comeau MR, Artis D. TSLP promotes IL-3-independent basophil hematopoiesis and type 2 inflammation. Nature. 2011 Aug;447(7363):229-33. PMID: 21841801. PMCID: PMC3263308.
2010
Hill DA, Artis D. Intestinal bacteria and the regulation of immune cell homeostasis. Annu Rev Immunol. 2010;28:623-67. doi: 10.1146/annurev-immunol-030409-101330.
Hill DA, Hoffmann C, Abt MC, Du Y, Kobuley D, Kirn TJ, Bushman FD, Artis D. Metagenomic analyses reveal antibiotic-induced temporal and spatial changes in intestinal microbiota with associated alterations in immune cell homeostasis. Mucosal Immunology. 2010 Mar;3(2):148-58. PMID: 19940845. PMCID: PMC2824244. Cited >250 times.
Hill DA, Desai SA. Malaria parasite mutants with altered erythrocyte permeability: a new drug resistance mechanism and important molecular tool. Future Microbiol. 2010 Jan;5(1):81-97. doi: 10.2217/fmb.09.109.
2009
Hill DA, Artis D. Maintaining diplomatic relations between mammals and beneficial microbial communities. Sci Signal. 2009 Nov 24;2(98):pe77. doi: 10.1126/scisignal.298pe77.
Hoffmann C, Hill DA, Minkah N, Kirn T, Troy A, Artis D, Bushman, F. Community-Wide Response of the Gut Microbiota to Enteropathogenic Citrobacter rodentium Infection Revealed by Deep Sequencing. Infection and Immunity. 2009 Oct;77(10):4668-78. PMID: 19635824. PMCID: PMC2747949.
2007
Alkhalil A, Hill DA, Desai SA. Babesia and plasmodia increase host erythrocyte permeability through distinct mechanisms. Cellular Microbiology. 2007 Apr;9(4):851-60. PMID: 17087736.
Staines HM, Alkhalil A, Allen RJ, De Jonge HR, Derbyshire E, Hill DA, et al. Electrophysiological studies of malaria parasite-infected erythrocytes: current status. Int J Parasitol. 2007 Apr;37(5):475-82. Epub 2007 Jan 9.
Hill DA, Pillai AD, Nawaz F, Hayton K, Doan L, Lisk G, Desai SA. A blasticidin S-resistant Plasmodium falciparum mutant with a defective plasmodial surface anion channel. Proceedings of the National Academy of Sciences USA. 2007 Jan;104(3):1063-8. PMID: 17213308. PMCID: PMC1783364. Cited >50 times.
Abstracts (includes Posters and Scientific Presentations)
2023
Paneru BD, Chini J, Miller J, Joannas LD, Henao-Mejia J, Tichenell PM, Merrick DM, Lim HW, Lazar M, Hill DA. Macrophage-derived miR-6236 potentiates adipocyte insulin signaling to prevent hyperglycemia during obesity. Poster presentation. Midwinter Conference of Immunologists. Asilomar, CA. Jan. 2023.
Gabryszewski SJ, Dudley J, Shu D, Faerber JA, Grundmeier RW, Fiks AG, Spergel JM, Hill DA. Features of pediatric eosinophilic esophagitis in a multi-state electronic health record-based cohort. Journal of Allergy and Clinical Immunology. AB274, Feb. 2023. Poster presentation. AAAAI Annual Meeting. San Antonio, TX. Feb. 2023.
Chini J, McCright S, Hill DA. Hepatic CD9 regulates adipose tissue inflammation and function during obesity. Poster presentation. AAP/ASCI/APSA Joint Meeting. Chicago, IL. Apr. 2023.
Grier AE, Hill DA. Severe, life-threatening hereditary angioedema of the larynx induced by ingestion of cold foods. Annals of Allergy, Asthma & Immunology. Poster presentation. ACAAI Annual Meeting. Anaheim, CA. Nov. 2023.
2022
Dilollo J, Pratt M, Rodriguez-Lopez EM, Spergel JM, Hill DA. Relative Antigenicity and HLA Locus Restriction of Milk Proteins in Eosinophilic Esophagitis. Oral presentation. Gordon Research Seminar in Food Allergy. Ventura, CA. Jan. 2022 (cancelled due to COVID).
Rodríguez-López EM, Dilollo J, Eisenlohr L, Hill DA. Esophageal Epithelial Cells Present Antigen on MHCII in an IFNy and Promoter IV-Dependent Manner. Journal of Allergy and Clinical Immunology. AB412, Feb. 2022. Oral presentation. AAAAI Annual Meeting. Phoenix, AZ. Feb. 2022.
Gabryszewski SJ, Dudley J, Grundmeier RW, Fiks AG, Hill DA. Analysis of a Multi-State Pediatric Birth Cohort Reveals Incidence of Pediatric Allergy. Journal of Allergy and Clinical Immunology. AB683, Feb. 2022. Oral presentation. AAAAI Annual Meeting. Phoenix, AZ. Feb. 2022.
2021
Gabryszewski SJ, Dudley J, Grundmeier, RW, Hill DA. Bioinformatic analysis of electronic birth cohort reveals distinct associations between early-life environmental factors and childhood allergic outcomes. Journal of Allergy and Clinical Immunology. 147(2);AB116, Feb. 2021. Poster presentation. AAAAI Annual Meeting. Virtual. Feb. 2021.
Dilollo J, Martin E, Spergel JM, Hill DA. Development of an antigen-specific T cell assay to identify food triggers in eosinophilic esophagitis. Journal of Allergy and Clinical Immunology. 147(2):AB164, Feb. 2021. Oral presentation. AAAAI Annual Meeting. AAAAI Annual Meeting. Virtual. Feb. 2021.
Floyd GC, Dudley J, Xiao R, Feudtner C, Taquechel K, Miller K, Henrickson SE, Hill DA, Kenyon CC. Prevalence of asthma in hospitalized and non-hospitalized children with COVID-19. Oral presentation. PAS Annual Meeting. Virtual. May 2021.
Diwadkar A, Sayed S, Taquechel K, Dudley JW, Grundmeier RW, Kenyon CK, Henrickson SE, Hill DA, Himes BE. COVID-19 in environmental, occupational, and population health. American Journal of Respiratory and Critical Care Medicine. 203:A3078, May 2021. Poster presentation. American Thoracic Society (ATS) Annual Meeting. Virtual. May 2021.
Ruffner MA, Hu A, Dilollo J, Benocek K, Shows D, Gluck M, Spergel JM, Ziegler SF, Hill DA, Cerosaletti K. Children and adults with eosinophilic esophagitis share a conserved interferon signature. Oral Presentation. FOCIS Annual Meeting. Virtual. Jun 2021.
Sterling J, Baumann B, Foshe S, Voigt AP, Guttha S, Alnemri A, McCright S, Chavali V, Hill DA, Ferrington DA, Stambolian D, Mullins RF, Merrick D, Dunaief JL. Inflammatory adipose activates nutritional immunity leading to retinal dysfunction. Investigative Ophthalmology & Visual Science. Vol.62, 265, Jun 2021. Poster presentation. ARVO Annual Meeting. Virtual. Jun 2021.
McCright S, Hill DA. Obesity Alters Pulmonary Macrophage Lipid Metabolism and Function During Asthma. Annals of Allergy, Asthma & Immunology. 127(5):S5, Nov 2021. Oral presentation. ACAAI Annual Meeting. New Orleans, LA. Nov 2021.
Alsaati N, Sandhu A, Kohut T, Patel P, Hill, DA. Peripheral eosinophilia in a patient with autoimmune hepatitis. Annals of Allergy, Asthma & Immunology. 127(5):S121, Nov 2021. Poster presentation. ACAAI Annual Meeting. New Orleans, LA. Nov 2021.
Lectures by Invitation
2023
Hill DA. Food-Specific Memory T Cell Responses for Management of IgE-Independent Eosinophilic Esophagitis. Hartwell Foundation Annual Meeting. Virtual. Sept 2023.
Hill DA. Interactions between diet and the immune system. Pfizer & Center for Immunity and Inflammation. Rutgers New Jersey Medical School. Newark, NJ. Sept 2023.
Hill DA. Immune regulation of Metabolic health. CMDB/GGB/MCBL Seminar Program. University of California, Riverside. Riverside, CA. Apr 2023.
2022
Hill DA. Food-Specific Memory T Cell Responses for Diagnosis and Monitoring of IgE-Independent Allergic Esophagitis. Hartwell Foundation Annual Meeting. Virtual. Sept 2022.
Hill DA. T cell responses in eosinophilic gastrointestinal diseases. Invited speaker. AAAAI 2022 Annual Meeting. Phoenix, AZ. Feb 2022.
2021
Hill DA. Allergy Myths! Debunked. Invited speaker. AAP 2021 Annual Meeting. Philadelphia, PA (talk canceled when conference held virtually due to COVID). Oct 2021.
Hill DA. Preventing the allergic march in children. Annenberg Center for Health Sciences. Rancho Mirage, CA. May 2021.
Editorials, Reviews, Chapters
2019
Hill DA*. Reflux and failure to thrive. In: Pediatric Allergy: A Case-Based Collection with MCQs, 1(20):101-105. 2019. ISBN 978-3-030-18281-6. DOI 10.1007/978-3-030-18282-3_20.