Andrew E. Weller, MD
Locations: Main Building
About Andrew E. Weller, MD
Titles
Psychiatrist
Certifications
Psychiatry – American Board of Psychiatry and Neurology
Child and Adolescent Psychiatry – American Board of Psychiatry and Neurology
Education & training
Medical Degree
MD - Drexel University College of Medicine, Philadelphia, PA
Residency
Child and Adolescent Psychiatry - Thomas Jefferson University Hospital, Philadelphia, PA
Psychiatry - Thomas Jefferson University Hospital, Philadelphia, PA
Publications
Publications
2024
Weller AE, Ferraro TN, Doyle GA, Reiner BC, Berrettini WH, Crist RC. Analysis of single-cell transcriptome data from a mouse model implicates protein synthesis dysfunction in schizophrenia. Genes Genomics. 2024 Sep;46(9):1071-1084. doi: 10.1007/s13258-024-01545-3. Epub 2024 Jul 31. PMID: 39083157.
2022
Weller AE, Ferraro TN, Doyle GA, Reiner BC, Crist RC, Berrettini WH. Single Nucleus Transcriptome Data from Alzheimer's Disease Mouse Models Yield New Insight into Pathophysiology. J Alzheimers Dis. 2022;90(3):1233-1247.
Weller AE, Doyle GA, Reiner BC, Crist RC, Berrettini WH. Analysis of differential gene expression and transcript usage in hippocampus of Apoe null mutant mice: Implications for Alzheimer's disease. Neurosci Res. 2022 Mar;176:85-89.
2021
Reiner BC, Doyle GA, Weller AE, Levinson RN, Rao AM, Perea ED, Namoglu E, Pigeon A, Arauco-Shapiro G, Weickert CS, Turecki G, Crist RC, Berrettini WH, Inherited L1 Retrotransposon Insertions Associated With Risk for Schizophrenia and Bipolar Disorder, Schizophr Bull Open. 2021 Jul 14; 2(1):sgab031.
Weller AE, Crist RC, Reiner BC, Doyle GA, Berrettini WH. Neonatal Opioid Withdrawal Syndrome (NOWS): A Transgenerational Echo of the Opioid Crisis. Cold Spring Harb Perspect Med. 2021 Mar 1;11(3):a039669.
2020
Reiner BC, Doyle GA, Weller AE, Levinson RN, Namoglu E, Pigeon A, Perea ED, Weickert CS, Turecki G, Mash DC, Crist RC, Berrettini WH. Restriction Enzyme Based Enriched L1Hs Sequencing (REBELseq): A Scalable Technique for Detection of Ta Subfamily L1Hs in the Human Genome. G3 (Bethesda). 2020 May 4;10(5):1647-1655.
2019
Metpally RP, Krishnamurthy S, Moran KM, Weller AE, Crist RC, Reiner BC, Doyle GA, Ferraro TN, Radhakrishna U, Bahado-Singh R, Troiani V, Berrettini WH. The imperative of clinical and molecular research on neonatal opioid withdrawal syndrome. Mol Psychiatry. 2019 Nov;24(11):1568-1571. Epub 2019 Sep 10.
2018
Elia J, Ungal G, Kao C, Ambrosini A, De Jesus-Rosario N, Larsen L, Chiavacci R, Wang T, Kurian C, Titchen K, Sykes B, Hwang S, Kumar B, Potts J, Davis J, Malatack J, Slattery E, Moorthy G, Zuppa A, Weller A, Byrne E, Li YR, Kraft WK, Hakonarson H. Fasoracetam in adolescents with ADHD and glutamatergic gene network variants disrupting mGluR neurotransmitter signaling. Nat Commun. 2018 Jan 16;9(1):4.
2011
Doyle GA, Dahl JP, Bloch PJ, Weller AE, Lohoff FW, Ferraro TN, Berrettini WH. Association study of polymorphisms in the autosomal mitochondrial complex I subunit gene, NADH dehydrogenase (ubiquinone) flavoprotein 2, and bipolar disorder. Psychiatr Genet. 2011 Feb;21(1):51-2.
2010
Bloch PJ, Weller AE, Doyle GA, Ferraro TN, Berrettini WH, Hodge R, Lohoff FW. Association analysis between polymorphisms in the myo-inositol monophosphatase 2 (IMPA2) gene and bipolar disorder. Prog Neuropsychopharmacol Biol Psychiatry. 2010 Dec 1;34(8):1515-9. Epub 2010 Aug 26.
Lohoff FW, Ferraro TN, Brodkin ES, Weller AE, Bloch PJ. Association between polymorphisms in the metallophosphoesterase (MPPE1) gene and bipolar disorder. Am J Med Genet B Neuropsychiatr Genet. 2010 Apr 5;153B (3):830-6.
2009
Bloch PJ, Nall AH, Weller AE, Ferraro TN, Berrettini WH, Kampman KM, Pettinati HM, Dackis CA, O'Brien CP, Oslin DW, Lohoff FW. Association analysis between polymorphisms in the dopamine D3 receptor (DRD3) gene and cocaine dependence. Psychiatr Genet. 2009 Oct;19(5):275-6.
2008
Lohoff FW, Weller AE, Bloch PJ, Nall AH, Ferraro TN, Kampman KM, Pettinati HM, Oslin DW, Dackis CA, O'Brien CP, Berrettini WH. Association between the catechol-O-methyltransferase Val158Met polymorphism and cocaine dependence. Neuropsychopharmacology. 2008 Dec;33(13):3078-84. Epub 2008 Aug 13.
Lohoff FW, Weller AE, Bloch PJ, Nall AH, Ferraro TN, Berrettini WH. Association between polymorphisms in the vesicle-associated membrane protein-associated protein A (VAPA) gene on chromosome 18p and bipolar disorder. J Neural Transm. 2008 Sep;115(9):1339-45. Epub 2008 Jul 30.
Lohoff FW, Bloch PJ, Weller AE, Nall AH, Doyle GA, Buono RJ, Ferraro TN, Kampman KM, Pettinati HM, Dackis CA, Oslin DW, O'Brien CP, Berrettini WH. Genetic variants in the cocaine- and amphetamine-regulated transcript gene (CARTPT) and cocaine dependence. Neurosci Lett. 2008 Aug 8;440(3):280-3. Epub 2008 May 24.
Lohoff FW, Weller AE, Bloch PJ, Buono RJ, Doyle GA, Ferraro TN, Berrettini WH. Association between polymorphisms in the vesicular monoamine transporter 1 gene (VMAT1/SLC18A1) on chromosome 8p and schizophrenia. Neuropsychobiology. 2008;57(1-2):55-60. Epub 2008 May 2.
Lohoff FW, Bloch PJ, Weller AE, Ferraro TN, Berrettini WH. Association analysis of the pituitary adenylate cyclase-activating polypeptide (PACAP/ADCYAP1) gene in bipolar disorder. Psychiatr Genet. 2008 Apr;18(2):53-8.
2006
Weller AE, Dahl JP, Lohoff FW, Kampman KM, Oslin DW, Dackis C, Ferraro TN, O'Brien CP, Berrettini WH. No association between polymorphisms in the prostate apoptosis factor-4 gene and cocaine dependence. Psychiatr Genet. 2006 Oct;16(5):193-6.
Dahl JP, Cubells JF, Ray R, Weller AE, Lohoff FW, Ferraro TN, Oslin DW, Kampman KM, Dackis C, Tang Y, Gelernter J, Kranzler HR, O'Brien CP, Berrettini WH. Analysis of variations in the tryptophan hydroxylase-2 (TPH2) gene in cocaine dependence. Addict Biol. 2006 Mar;11(1):76-83.
Weller AE, Dahl JP, Lohoff FW, Ferraro TN, Berrettini WH. Analysis of variations in the NAPG gene on chromosome 18p11 in bipolar disorder. Psychiatr Genet. 2006 Feb;16(1):3-8.
2005
Dahl JP, Kampman KM, Oslin DW, Weller AE, Lohoff FW, Ferraro TN, O'Brien CP, Berrettini WH. Association of a polymorphism in the Homer1 gene with cocaine dependence in an African American population. Psychiatr Genet. 2005 Dec;15(4):277-83.
Dahl JP, Weller AE, Kampman KM, Oslin DW, Lohoff FW, Ferraro TN, O'Brien CP, Berrettini WH. Confirmation of the association between a polymorphism in the promoter region of the prodynorphin gene and cocaine dependence. Am J Med Genet B Neuropsychiatr Genet. 2005 Nov 5;139B (1):106-8.
Abstracts (includes Posters and Scientific Presentations)
2023
Ferraro TN, Reiner BC, Chehimi SN, Doyle GA, Weller AE, Batterman AI, Nguyen DP, Williams A, Keck TM, Berrettini WH, Buono RJ, Crist RC. Antidepressant treatment alters cell type-specific gene expression pathways related to plasticity in mouse hippocampus. Program No. PSTR100.06. 2023 Neuroscience Meeting Planner. Washington, DC: Society for Neuroscience, 2023. Online.
Weller AE, Ferraro TN, Doyle GA, Reiner BC, Berrettini WH, Crist RC. Differential gene expression and transcript usage in a mouse model promotes characterization of schizophrenia pathophysiology. Program No. PSTR177.12. 2023 Neuroscience Meeting Planner. Washington, DC: Society for Neuroscience, 2023. Online.
2022
Ferraro TN, Reiner BC, Doyle GA, Weller AE, Batterman AI, Berrettini WH, Buono RJ, Crist R. Electroconvulsive shock selectively alters the transcriptome of hippocampal cells in mice. Program No. 364.18. 2022 Neuroscience Meeting Planner. San Diego, CA: Society for Neuroscience, 2022. Online.
Weller A, Ferraro T, Doyle G, Reiner B, Crist R, Berrettini W. Differential gene expression and transcript usage in mouse models implicates cell types in Alzheimer’s disease pathology. Program No. 613.25. 2022 Neuroscience Meeting Planner. San Diego, CA: Society for Neuroscience, 2022. Online.
Reiner B, Dávila E, Weller A, Zhang Y, Arauco-Shapiro G, Ben Nathan J, Ragnini K, Ferraro T, Berrettini W, Schmidt H, Crist R, 2022. W123. Cell type-specific transcript usage in the rat nucleus accumbens after acute or chronic morphine exposure. European Neuropsychopharmacology 63, e163.
2021
Weller AE, Doyle GA, Reiner BC, Crist RC, Berrettini WH. Differential gene expression and transcript usage at single-cell resolution in a mouse model of Alzheimer’s disease. Program No. 192.09. 2021 Neuroscience Meeting Planner. Chicago, IL: Society for Neuroscience, 2021. Online.
Reiner B, Crist R, Stein L, Weller A, Doyle G, Arauco-Shapiro G, Turecki G, Ferraro T, Hayes M, Berrettini W, 2021. W72. Single-nuclei transcriptomics of schizophrenia prefrontal cortex primarily implicates neuronal subtypes. European Neuropsychopharmacology 51, e182-e183.