What is congenital hepatic fibrosis?

Congenital hepatic fibrosis (CHF) is an inherited disease that both the liver and kidneys. The condition can cause the liver, kidneys and bile ducts to form abnormally before birth and may also cause fibrosis and scarring on the liver.

Congenital hepatic fibrosis is associated with autosomal recessive polycystic kidney disease (ARPKD) and Caroli syndrome.

At The Children's Hospital of Philadelphia, children with congenital hepatic fibrosis are treated by hepatologists and gastroenterologists in the Biesecker Pediatric Liver Center and the Division of Gastroenterology (GI), Hepatology and Nutrition.