Children’s Hospital of Philadelphia (CHOP) has announced the establishment of the Punchard Family Endowed Chair in Translational Sarcoma Research. Patrick J. Grohar, MD, PhD, an attending physician with the Cancer Center and the Director of Translational Research with the Center for Childhood Cancer Research at CHOP, has been named the inaugural chair holder.

CHOP played an instrumental role in leading one of two clinical trials that led to the approval of Xalkori® for unresectable, recurrent, or refractory ALK-positive IMT.

Read this case study about a patient who received treatment for osteosarcoma and underwent limb salvage surgery at Children’s Hospital of Philadelphia.

This case study highlights a multimodal approach to surgical management of osteosarcomas in young children, maximizing control while providing a functional limb that will grow with the child.

Van Nes rotationplasty surgery for osteosarcoma is a “functional amputation” in which the the foot is rotated 180 degrees on the vertical axis and the ankle becomes a functioning knee joint.

CHOP has been at the forefront of developing cell therapy to treat ALL. Some next steps include initiating clinical trials for AML and, ultimately, making this treatment work for solid tumors.

Using the case of a 14-year-old male diagnosed with osteosarcoma, we discuss the diagnosis and treatment of bone cancer with the goal of preserving limbs and functions.

We present three cases of Ewing sarcoma treated at Children's Hospital of Philadelphia (CHOP), where a multidisciplinary team of experts focuses on curing the patients as well as preserving limb function and growth potential.

CHOP recently launched a Bone and Soft Tissue Tumor Program, a collaboration between teams from Orthopedics and Oncology.