Sickle Cell and Red Cell Disorders Curative Therapy Center (CuRED)
The Sickle Cell and Red Cell Disorders Curative Therapy Center (CuRED) offers integrated and coordinated care from multiple pediatric specialists for children with sickle cell disease, thalassemia, and other red cell disorders. The CuRED team provides comprehensive evaluation and cutting-edge treatment that is customized to each patient and family, and guides children from management of a chronic disease to exploring the potential for a curative therapy.
FDA Approves Two Gene Therapies for Sickle Cell Disease
The Food and Drug Administration (FDA) has approved CASGEVY™ (exagamglogene autotemcel) and LYFGENIA™ (lovotibeglogene autotemcel), the first two gene therapies for the treatment of sickle cell disease in patients 12 years and older with recurrent vaso-occlusive crises (VOCs).
Why Choose Us?
This is the first clinical center in the United States to offer a family-focused, integrated care model to help patients with red blood cell disorders on their journey from chronic disease to cure. The breadth and depth of expertise at CHOP makes us uniquely positioned to offer this level of multidisciplinary care.
Blood and Marrow Transplant vs. Gene Therapy
CHOP offers many curative therapy options to our patients. Broadly, these treatments fall into two categories: blood or bone marrow transplant and experimental gene therapy. View this guide to learn about the differences between these two therapeutic options.
Conditions We Treat
Our Team
Coordinated care for children with red blood cell disorders is provided by a multidisciplinary team of providers from hematology, stem cell transplant, cardiology, pulmonology, neurology, general surgery, orthopaedics, and radiology.