Red Blood Cell Genotyping in Sickle Cell Disease

Study title

Red Blood Cell Genotyping in Sickle Cell Disease

Study objectives

Determine the prevalence of altered RH genes in SCD patients, determine if they are associated with alloimmunization, and determine other previously unidentified risk factors of alloimmunization.

Determine the prevalence of altered RH genes in the general African-American population to test the feasibility of RBC genetic matching for SCD patients.

Eligibility

All SCD patients.

PI: Dr. Stella Chou

SC: Tannoa Jackson, Henrietta Enninful–Eghan

Sponsor: The Doris Duke Charitable Foundation

Next Steps
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Sickle Cell Center
Buerger Center for Advanced Pediatric Care
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