Areas of Expertise:
Cardiac Arrest and Resuscitation Simulation, Advanced Education and Innovation Novel Treatments for ischemia/reperfusion and hopoxemia/ischemia, Just-in-time and just-in-place health care provider training, Modulation of the immune response with enteral nutrition, Clinical Trials in Pediatric Critical Care, Regional, National and International medicine
Appointments and Referrals: 1-800-TRY-CHOP
Dr. Nadkarni is medical and research director of the Center for Simulation, Advanced Education and Innovation at The Children’s Hospital of Philadelphia. He holds the institution’s Endowed Chair in Pediatric Critical
Care Medicine and has been an international leader for development and implementation of critical care and resuscitation science in both resource-rich and resource-poor environments.
He has studied and is regularly invited to lecture on these topics at leading academic centers around the world.
Dr. Nadkarni previously served as director of CHOP’s Pediatric Critical Care Medicine fellowship program, the first such program established in the world, and has mentored and trained more than 100 physicians, advanced practice nurses, post-doctorate fellows, and international trainees in the course of his career. The Center for Simulation, Advanced Education and Innovation at CHOP collaborates with scientists, engineers, industry, and human factors specialists to develop state-of-the art simulation techniques and simulators, provides advanced training in highly-realistic simulated environments, and offers consultation and training programs at the local, regional, national and international levels.
Dr. Nadkarni is an active and influential participant in the most influential international societies and organizations in this field. For more than 20 years, he has volunteered with Operation Smile International to provide craniofacial surgical repair for more than 2,000 children in resource-limited settings. He serves on the Board of Directors of the World Federation of Pediatric Intensive and Critical Care Societies, has chaired the American Heart Association’s International Committee, and currently is the chairman of the International Liaison Committee on Resuscitation (which links the American Heart Association and resuscitation councils of Canada, Europe, Asia, Australia, New Zealand, Latin America and Africa).
- Education and Training
MD - University of Maryland School of Medicine, College Park, MD
Children's National Medical Center, Washington, DC
Children's National Medical Center, Washington, DC
Pediatric Critical Care - Children's National Medical Center, Washington, DC
PediatricsCritical Care Medicine
Georgetown University, Washington, D.C.
- Titles and Academic Titles
Medical Director, Center for Simulation, Advanced Education and Innovation
Endowed Chair, Critical Care Medicine
Associate Director, Center for Resuscitation Science, Perelman School of Medicine at the University of Pennsylvania
- Centers and Programs
Roberts K, Srinivasan V, Niles DE, Eilevstjønn J, Tyler L, Boyle L, Bishnoi R, Ferry S, Nysæther J, Stavland M, Litman RS, Helfaer M, Nadkarni V. Does change in thoracic impedance measured via defibrillator electrode pads accurately detect ventilation breaths in children? Resuscitation. 2010 Nov;81(11):1544-9. Epub 2010 Aug 25. Read abstract.
Meaney PA, Topjian AA, Chandler HK, Botha M, Soar J, Berg RA, Nadkarni VM. Resuscitation training in developing countries: A systematic review. Resuscitation. 2010 Aug 18. [Epub ahead of print] Read abstract.
Niles DE, Nishisaki A, Sutton RM, Brunner S, Stavland M, Mahadevaiah S, Meaney PA, Maltese MR, Berg RA, Nadkarni VM. Analysis of transthoracic impedance during real cardiac arrest defibrillation attempts in older children and adolescents: Are stacked-shocks appropriate? Resuscitation. 2010 Aug 12. [Epub ahead of print] Read abstract.
Nishisaki A, Donoghue AJ, Colborn S, Watson C, Meyer A, Brown CA 3rd, Helfaer MA, Walls RM, Nadkarni VM. Effect of just-in-time simulation training on tracheal intubation procedure safety in the pediatric intensive care unit. Anesthesiology. 2010 Jul;113(1):214-23. Read abstract
Sutton RM, Niles D, Nysaether J, Arbogast KB, Nishisaki A, Maltese MR, Bishnoi R, Helfaer MA, Nadkarni V, Donoghue A. Pediatric CPR quality monitoring: analysis of thoracic anthropometric data. Resuscitation. 2009 Oct;80(10):1137-41. Epub 2009 Jul 31. Read abstract.
Rake AJ, Srinivasan V, Nadkarni V, Kaptan R, Newth CJ. Glucose variability and survival in critically ill children: Allostasis or harm? Pediatr Crit Care Med. 2010 Jul 9. [Epub ahead of print]. Read abstract
Bembea MM, Nadkarni VM, Diener-West M, Venugopal V, Carey SM, Berg RA, Hunt EA; for the American Heart Association National Registry of Cardiopulmonary Resuscitation Investigators. Temperature patterns in the early postresuscitation period after pediatric inhospital cardiac arrest* Pediatr Crit Care Med. 2010 Apr 28. [Epub ahead of print]. Read abstract
Meyer A, Nadkarni V, Pollock A, Babbs C, Nishisaki A, Braga M, Berg RA, Ades A. Evaluation of the Neonatal Resuscitation Program's recommended chest compression depth using computerized tomography imaging. Resuscitation. 2010 May;81(5):544-8. Epub 2010 Mar 12. Read abstract.
Srinivasan V, Nadkarni VM, Helfaer MA, Carey SM, Berg RA; American Heart Association National Registry of Cardiopulmonary Resuscitation Investigators.Childhood obesity and survival after in-hospital pediatric cardiopulmonary resuscitation. Pediatrics. 2010 Mar;125(3):e481-8. Epub 2010 Feb 22. Read abstract
Donoghue AJ, Durbin DR, Nadel FM, Stryjewski GR, Kost SI, Nadkarni VM. Perception of realism during mock resuscitations by pediatric housestaff: the impact of simulated physical features. Simul Healthc. 2010 Feb;5(1):16-20. Read abstract
Topjian AA, Localio AR, Berg RA, Alessandrini EA, Meaney PA, Pepe PE, Larkin GL, Peberdy MA, Becker LB, Nadkarni VM; American Heart Association National Registry of Cardiopulmonary Resuscitation Investigators. Women of child-bearing age have better inhospital cardiac arrest survival outcomes than do equal-aged men. Crit Care Med. 2010 May;38(5):1254-60. Read abstract.
Topjian A, Hutchins L, Diliberto MA, Abend N, Ichord R, Helfaer M, Berg RA, Nadkarni V. Induction and maintenance of therapeutic hypothermia after pediatric cardiac arrest: Efficacy of a surface cooling protocol. Pediatr Crit Care Med. 2010 Apr 28. [Epub ahead of print]. Read abstract
Pirzadeh A, Schears G, Pastuszko P, Liu H, Kubin J, Reade E, Mendoza-Paredes A, Greeley W, Nadkarni V, Wilson DF, Pastuszko A. Effect of deep hypothermic circulatory arrest followed by low-flow cardiopulmonary bypass on brain metabolism in newborn piglets: Comparison of pH-stat and alpha-stat management. Pediatr Crit Care Med. 2010 Jul 1. Read abstract
Kilbaugh TJ, Srinivasan V, Berg RA, Nadkarni VM. Propensity, prophecy, and perplexity: does in-hospital extracorporeal cardiopulmonary resuscitation really make a difference? Resuscitation. 2010 Jul;81(7):786-7. Epub 2010 Jun 9. No abstract available. Read abstract.
Sutton RM, Niles D, Nysaether J, Stavland M, Thomas M, Ferry S, Bishnoi R, Litman R, Allen J, Srinivasan V, Berg RA, Nadkarni VM. Effect of residual leaning force on intrathoracic pressure during mechanical ventilation in children. Resuscitation. 2010 Jul;81(7):857-60. Epub 2010 Apr 20. Read abstract
Sutton RM, Maltese MR, Niles D, French B, Nishisaki A, Arbogast KB, Donoghue A, Berg RA, Helfaer MA, Nadkarni V. Quantitative analysis of chest compression interruptions during in-hospital resuscitation of older children and adolescents. Resuscitation. 2009 Nov;80(11):1259-63. Epub 2009 Sep 4. Read abstract.
Arbogast KB, Nishisaki A, Balasubramanian S, Nysaether J, Niles D, Sutton RM, Roberts KE, Nadkarni L, Boulet J, Maltese MR, Nadkarni VM. Expert clinical assessment of thorax stiffness of infants and children during chest compressions. Resuscitation. 2009 Oct;80(10):1187-91. Epub 2009 Aug 20 Read abstract.
Sutton RM, Niles D, Nysaether J, Abella BS, Arbogast KB, Nishisaki A, Maltese MR, Donoghue A, Bishnoi R, Helfaer MA, Myklebust H, Nadkarni V. Quantitative analysis of CPR quality during in-hospital resuscitation of older children and adolescents. Pediatrics. 2009 Aug;124(2):494-9. Epub 2009 Jul 5. Read abstract.
Niles D, Sutton RM, Donoghue A, Kalsi MS, Roberts K, Boyle L, Nishisaki A, Arbogast KB, Helfaer M, Nadkarni V. "Rolling Refreshers": a novel approach to maintain CPR psychomotor skill competence. Resuscitation. 2009 Aug;80(8):909-12. Epub 2009 May 20. Read abstract.
Nishisaki A, Nysaether J, Sutton R, Maltese M, Niles D, Donoghue A, Bishnoi R, Helfaer M, Perkins GD, Berg R, Arbogast K, Nadkarni V. Effect of mattress deflection on CPR quality assessment for older children and adolescents. Resuscitation. 2009 May;80(5):540-5. Epub 2009 Apr 1. Read abstract.
Niles D, Nysaether J, Sutton R, Nishisaki A, Abella BS, Arbogast K, Maltese MR, Berg RA, Helfaer M, Nadkarni V. Leaning is common during in-hospital pediatric CPR, and decreased with automated corrective feedback. Resuscitation. 2009 May;80(5):553-7. Epub 2009 Mar 18. Read abstract.