Mark P. Johnson, MD, MS

Mark Johnson, MD, is the director of Obstetrical Services at the Center for Fetal Diagnosis and Treatment at The Children’s Hospital of Philadelphia.

Areas of Expertise: Fetal obstructive uropathy, Prenatal diagnosis and therapy
Locations: Main Campus
Phone: 800-468-8376

  • Background

    Dr. Johnson is the Director of Obstetrical Services at the Center for Fetal Diagnosis and Treatment (CFDT) at The Children’s Hospital of Philadelphia (CHOP). He holds the George Loeb Harrison Endowed Research Chair in Fetal Therapy. He also serves as professor in the Departments of Surgery, Obstetrics & Gynecology, and Pediatrics at the University of Pennsylvania School of Medicine.

    A true innovator in the fields of Obstetrics and Fetal Medicine, Dr. Johnson helped develop fetoscopic surgical procedures for twin-twin transfusion syndrome and prenatal treatment of fetal lower urinary tract obstructions. He has made significant discoveries examining long term developmental outcomes in children who have undergone fetal spina bifida repair, including demonstrated improvement in motor function in the lower extremities and a decreased need for shunting.

    A practiced geneticist, Dr. Johnson collaborates with Alan Flake, MD, FACS, FAAP, to advance techniques for prenatal gene and stem cell therapy.

    An invaluable member of the CFDT team, Dr. Johnson specializes in fetal obstructive uropathy and prenatal diagnosis and therapy. He says he is continually inspired by the diverse patient population at the CFDT and the often challenging conditions they face. His goal is to create the best possible outcomes for every patient and patient family.

    “I am proud of the 13 years I have been at CHOP. The CFDT has really made big advances in the multidisciplinary imaging and evaluation of pregnancies complicated by anomalies,” he says. “We continue to develop and refine techniques to treat complicated twin pregnancies, congenital tumors, urinary tract obstructions and inherited genetic diseases and improve survival rates and long term outcomes through stem cell and gene therapy.”

    Dr. Johnson graduated magna cum laude from Concordia College with a BA in Biology and he earned his medical degree from University of Minnesota Medical School, Minneapolis, MN. In 1980, he received a Masters in Science in Medical Genetics at the University of Minnesota in Minneapolis.

    Dr. Johnson completed his Obstetrics and Gynecology residency at University of Michigan Medical School and his Reproductive Genetics fellowship at Wayne State University School of Medicine, Detroit, MI.

    Prior to his appointment at CHOP, Dr. Johnson served as the Associate Director in the Division of Reproductive Genetics at Wayne State University School of Medicine and Hutzel Hospital, both in Detroit, MI. He is board certified in medical and clinical genetics and in obstetrics and gynecology. 

  • Education and Training

    Medical School

    MD - University of Minnesota School of Medicine, Minneapolis, MN

    Residency

    Obstetrics and Gynecology - University of Michigan Medical School, Ann Arbor, MI

    Fellowship

    Reproductive Genetics - Wayne State University School of Medicine, Detroit, MI

    Board Certification

    Clinical Genetics
    Obstetrics and Gynecology

    Graduate Degree

    MS in Medical Genetics - University of Minnesota School of Medicine, Minneapolis, MN

  • Titles and Academic Titles

    Attending Physician

    Obstetrical Director, Center for Fetal Diagnosis and Treatment

    George Lieb Harrison Endowed Chair in Fetal Therapy

    Professor of Surgery, Obstetrics and Gynecology and Pediatrics, Perelman School of Medicine at the University of Pennsylvania

  • Conditions Treated
  • Centers and Programs
  • Publications

    Papers

    2012

    Danzer E, Gerdes M, Bebbington MW, Koh J, Adzick SN, Johnson MP. Fetal myelomeningocele surgery: preschool functional status using the Functional Independence Measure for children (WeeFIM). Childs Nerv Syst. 2011 Jul;27(7):1083-8. Epub 2011 Feb 16. Cited in PubMed; PMID:21327591. Read the abstract

    Laje P, Johnson MP, Howell LJ, Bebbington MW, Hedrick HL, Flake AW, et al. Ex utero intrapartum treatment in the management of giant cervical teratomas. J Pediatr Surg. 2012 Jun;47(6):1208-16. Cited in Pub; PMID:22703795. Read the abstract

    2011

    Adzick NS, Thom EA, Spong CY, Brock III JW, Burrows PK, Johnson MP, Howell LJ, Farrell JA, Dabrowiak ME, Sutton LN, Gupta N, Tulipan NB, D'Alton ME, Farmer DL for the MOMS Investigators. A Randomized Trial of Prenatal versus Postnatal Repair of Myelomeningocele. NEJM. Online first. 9 Feb 2011. Read the article

    2010

    Danzer E, Finkel R, Gerdes M, Schwartz EM, Rintoul NN, Adzick NS, Johnson MP. The relationship of seizure activity and chronic epilepsy in early infancy and short-term neurodevelopmental outcome following fetal myelomeningocele closure. Neuropediatrics. 2010 Jun;41(3):140-3. Epub 2010 Sep 21. Read the abstract

    Roybal JL, Liechty KW, Hedrick HL, Bebbington MW, Johnson MP, Coleman BG, Adzick NS, Flake AW. Predicting the severity of congenital high airway obstruction syndrome. J Pediatr Surg. 2010 Aug;45(8):1633-9. Read the abstract

    Tran KM, Johnson MP, Almeida-Chen GM, Schwartz AJ. The Fetus as Patient. Anesthesiology. Epub 2010 Jul 6. No abstract available. Read the abstract

    Danzer E, Gerdes M, Bebbington MW, Zarnow DM, Adzick NS, Johnson MP. Preschool neurodevelopmental outcome of children following fetal myelomeningocele closure. Am J Obstet Gynecol. 2010 May;202(5):450.e1-9. Epub 2010 Mar 29. Read the abstract

    Wilson RD, Lemerand K, Johnson MP, Flake AW, Bebbington M, Hedrick HL, Adzick NS. Reproductive outcomes in subsequent pregnancies after a pregnancy complicated by open maternal-fetal surgery (1996-2007). Am J Obstet Gynecol. 2010 May 27. Read the abstract

    Servaes S, Hernandez A, Gonzalez L, Victoria T, Johnson M, Jaramillo D, Christopher Edgar J, Johnson A. Fetal MRI of clubfoot associated with myelomeningocele.Pediatr Radiol. Epub 2010 May 20. Read the abstract.

    Johnson MP; NAFTNet. The North American Fetal Therapy Network (NAFTNet): a new approach to collaborative research in fetal diagnosis and therapy. Semin Fetal Neonatal Med. 2010 Feb;15(1):52-7. Epub 2009 Jun 24. Read the abstract