Holly L. Hedrick, MD, FACS

Holly Hedrick, MD, is an attending pediatric and fetal surgeon at The Children’s Hospital of Philadelphia.

Areas of Expertise: Clinical applications of fetal diagnosis and therapy, ECMO, Laparoscopy and thoracoscopy, Neonatal Surgery, Oncology, Thoracic Surgery
Locations: Main Campus; Specialty Care & Surgery Center, Exton
Phone: 215-590-2730

  • Background

    Dr. Holly Hedrick is an attending surgeon in the Division of Pediatric General, Thoracic and Fetal Surgery at The Children’s Hospital of Philadelphia (CHOP). She is also the surgical director of the Extracorporeal Membrane Oxygenation (ECMO) Program, co-director of the Neonatal Surgery Team and director of the Pulmonary Hypoplasia Program. In addition, she is an investigator in the Center for Fetal Research and an associate professor of surgery at the University of Pennsylvania School of Medicine.

    Dr. Hedrick completed her pediatric surgery fellowship at CHOP and joined the staff as an attending surgeon 1999. “I felt grateful and honored to be trained at CHOP,” she says. “It is a dream come true to work here.” Dr. Hedrick’s areas of interest include neonatal surgery, ECMO, thoracic surgery, and minimally invasive techniques including laparoscopy and thoracoscopy.

    Her clinical specialty is treating children with congenital diaphragmatic hernia (CDH), a birth defect in which a hole in the diaphragm allows abdominal organs to migrate into the chest, restricting development of the lungs. Concerned with improving outcomes after surgical repair for these fragile infants, who suffer long-term complications including pulmonary hypoplasia, Dr. Hedrick sought to create a specialized program offering the most complete and current care tailored to the specific needs of patients with compromised lung function. The result was the Hospital’s unique Pulmonary Hypoplasia Program (PHP), founded in 2004, which unites specialists from various disciplines including neonatology, cardiology, pulmonology, audiology and gastroenterology, to provide comprehensive care for CDH patients well into school age. Today, more than 230 patients are followed in the PHP Program.

    “It’s been thrilling to work with this truly interdisciplinary team,” she says. “We are very challenged by these diagnoses, but we find it rewarding to see these babies through. It’s not enough to deliver a survivor. We want to give them a high quality of life.”

    Dr. Hedrick earned her bachelor’s degree from Indiana University and her medical degree from Duke University School of Medicine. She completed her general surgery residency at Brigham & Women’s Hospital/Harvard Medical School and her residency and fellowship in pediatric surgery at The Children’s Hospital of Philadelphia. Dr. Hedrick also completed research fellowships at Duke University School of Medicine and Harvard Medical School.

    To contact the Center for Fetal Diagnosis and Treatment, call 1-800-468-8376 (1-800-IN-UTERO).

  • Education and Training

    Medical School

    MD - Duke University School of Medicine, Durham, NC

    Internship

    General Surgery - Brigham and Women's Hospital, Boston, MA

    Residency

    Pediatric Surgery - The Children's Hospital of Philadelphia, Philadelphia, PA

    Fellowship

    Research - Indiana University School of Medicine Biomedical Research Program, Krannert Institute of Cardiology, Bloomington, IN
    Research - Duke University School of Medicine, Surgical Oncology Research Facility, Durham, NC
    Research - Department of P

    Board Certification

    Pediatric Surgery
    Surgery

  • Titles and Academic Titles

    Attending Surgeon

    Surgical Director, ECMO Program

    Co-director, Neonatal Surgery Team

    Director, Pulmonary Hypoplasia Program

    Associate Professor of Surgery, Perelman School of Medicine at the University of Pennsylvania

  • Conditions Treated
  • Centers and Programs
  • Publications

    Papers

    2012

    Danzer E, Zarnow D, Gerdes M, D'Agostino JA, Siegle J, Bebbington MW, et al. Abnormal brain development and maturation on magnetic resonance imaging in survivors of severe congenital diaphragmatic hernia. J Pediatr Surg. 2012 Mar;47(3):453-61. Cited in PubMed; PMID:22424337. Read the abstract

    Laje P, Johnson MP, Howell LJ, Bebbington MW, Hedrick HL, Flake AW, et al. Ex utero intrapartum treatment in the management of giant cervical teratomas. J Pediatr Surg. 2012 Jun;47(6):1208-16. Cited in PubMed; PMID:22703795. Read the abstract 

    2010

    Danzer E, Gerdes M, Bernbaum J, D'Agostino J, Bebbington MW, Siegle J, Hoffman C, Rintoul NE, Flake AW, Adzick NS, Hedrick HL. Neurodevelopmental outcome of infants with congenital diaphragmatic hernia prospectively enrolled in an interdisciplinary follow-up program. J Pediatr Surg. 2010 Sep;45(9):1759-66. Read the abstract.

    Roybal JL, Liechty KW, Hedrick HL, Bebbington MW, Johnson MP, Coleman BG, Adzick NS, Flake AW. Predicting the severity of congenital high airway obstruction syndrome. J Pediatr Surg. 2010 Aug;45(8):1633-9. Read the abstract.

    Wilson RD, Lemerand K, Johnson MP, Flake AW, Bebbington M, Hedrick HL, Adzick NS. Reproductive outcomes in subsequent pregnancies after a pregnancy complicated by open maternal-fetal surgery (1996-2007). Am J Obstet Gynecol. 2010 May 27. Read the abstract

    Danzer E, Gerdes M, D'Agostino JA, Bernbaum J, Siegle J, Hoffman C, Rintoul NE, Liechty KW, Flake AW, Adzick NS, Hedrick HL. Prospective, interdisciplinary follow-up of children with prenatally diagnosed giant omphalocele: short-term neurodevelopmental outcome. J Pediatr Surg. 2010 Apr;45(4):718-23. Read the abstract

    Hedrick HL. Management of prenatally diagnosed congenital diaphragmatic hernia. Semin Fetal Neonatal Med. 2010 Feb;15(1):21-7. Epub 2009 Nov 2. Review. Read the abstract