Diabetes Type 1 with Acute Illness Clinical Pathway — Emergency Department

Insulin Chart
Type of Insulin	Brand Name	May Be Mixed With	Onset	Peak	Duration
Rapid Acting (Prandial or Correction)
Aspart	Novolog^®	NPH	10-20 minutes	1-3 hours	3-5 hours
Short Acting (Prandial or Correction)
Regular	Novolin R	NPH	30-60 minutes	2-4 hours	4-8 hours
Intermediate Acting (Basal)
NPH	Novolin N	Aspart, Regular	1-2 hours	6-14 hours	16-24 hours
NPH/Regular	Novolin 70/30	DO NOT MIX	0.5 hour	2-12 hours	18-24 hours
Long Acting (Basal)
Glargine	Lantus^®	DO NOT MIX	2-4 hours	No peak	24 hours

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The clinical pathways are based upon publicly available medical evidence and/or a consensus of medical practitioners at The Children’s Hospital of Philadelphia (“CHOP”) and are current at the time of publication. These clinical pathways are intended to be a guide for practitioners and may need to be adapted for each specific patient based on the practitioner’s professional judgment, consideration of any unique circumstances, the needs of each patient and their family, and/or the availability of various resources at the health care institution where the patient is located.

Accordingly, these clinical pathways are not intended to constitute medical advice or treatment, or to create a doctor-patient relationship between/among The Children’s Hospital of Philadelphia (“CHOP”), its physicians and the individual patients in question. CHOP does not represent or warrant that the clinical pathways are in every respect accurate or complete, or that one or more of them apply to a particular patient or medical condition. CHOP is not responsible for any errors or omissions in the clinical pathways, or for any outcomes a patient might experience where a clinician consulted one or more such pathways in connection with providing care for that patient.